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Page 1
Use of opportunistic clinical data and a population pharmacokinetic model to support dosing of clindamycin for premature infants to adolescents.
Gonzalez D, Melloni C, Yogev R, Poindexter BB, Mendley SR, Delmore P, Sullivan JE, Autmizguine J, Lewandowski A, Harper B, Watt KM, Lewis KC, Capparelli EV, Benjamin DK Jr, Cohen-Wolkowiez M; Best Pharmaceuticals for Children Act – Pediatric Trials Network Administrative Core Committee. Gonzalez D, et al. Among authors: delmore p. Clin Pharmacol Ther. 2014 Oct;96(4):429-37. doi: 10.1038/clpt.2014.134. Epub 2014 Jun 20. Clin Pharmacol Ther. 2014. PMID: 24949994 Free PMC article. Clinical Trial.
Characterization of the population pharmacokinetics of ampicillin in neonates using an opportunistic study design.
Tremoulet A, Le J, Poindexter B, Sullivan JE, Laughon M, Delmore P, Salgado A, Ian-U Chong S, Melloni C, Gao J, Benjamin DK Jr, Capparelli EV, Cohen-Wolkowiez M; Administrative Core Committee of the Best Pharmaceuticals for Children Act-Pediatric Trials Network. Tremoulet A, et al. Among authors: delmore p. Antimicrob Agents Chemother. 2014 Jun;58(6):3013-20. doi: 10.1128/AAC.02374-13. Epub 2014 Mar 10. Antimicrob Agents Chemother. 2014. PMID: 24614374 Free PMC article. Clinical Trial.
Clindamycin Pharmacokinetics and Safety in Preterm and Term Infants.
Gonzalez D, Delmore P, Bloom BT, Cotten CM, Poindexter BB, McGowan E, Shattuck K, Bradford KK, Smith PB, Cohen-Wolkowiez M, Morris M, Yin W, Benjamin DK Jr, Laughon MM. Gonzalez D, et al. Among authors: delmore p. Antimicrob Agents Chemother. 2016 Apr 22;60(5):2888-94. doi: 10.1128/AAC.03086-15. Print 2016 May. Antimicrob Agents Chemother. 2016. PMID: 26926644 Free PMC article.
Population Pharmacokinetics of Trimethoprim-Sulfamethoxazole in Infants and Children.
Autmizguine J, Melloni C, Hornik CP, Dallefeld S, Harper B, Yogev R, Sullivan JE, Atz AM, Al-Uzri A, Mendley S, Poindexter B, Mitchell J, Lewandowski A, Delmore P, Cohen-Wolkowiez M, Gonzalez D; the Pediatric Trials Network Steering Committee. Autmizguine J, et al. Among authors: delmore p. Antimicrob Agents Chemother. 2017 Dec 21;62(1):e01813-17. doi: 10.1128/AAC.01813-17. Print 2018 Jan. Antimicrob Agents Chemother. 2017. PMID: 29084742 Free PMC article.
Population Pharmacokinetics of Intramuscular and Intravenous Ketamine in Children.
Hornik CP, Gonzalez D, van den Anker J, Atz AM, Yogev R, Poindexter BB, Ng KC, Delmore P, Harper BL, Melloni C, Lewandowski A, Gelber C, Cohen-Wolkowiez M, Lee JH; Pediatric Trial Network Steering Committee. Hornik CP, et al. Among authors: delmore p. J Clin Pharmacol. 2018 Aug;58(8):1092-1104. doi: 10.1002/jcph.1116. Epub 2018 Apr 20. J Clin Pharmacol. 2018. PMID: 29677389 Free PMC article.
Population Pharmacokinetics of Metoclopramide in Infants, Children, and Adolescents.
Ge S, Mendley SR, Gerhart JG, Melloni C, Hornik CP, Sullivan JE, Atz A, Delmore P, Tremoulet A, Harper B, Payne E, Lin S, Erinjeri J, Cohen-Wolkowiez M, Gonzalez D; Best Pharmaceuticals for Children Act - Pediatric Trials Network Steering Committee. Ge S, et al. Among authors: delmore p. Clin Transl Sci. 2020 Nov;13(6):1189-1198. doi: 10.1111/cts.12803. Epub 2020 May 27. Clin Transl Sci. 2020. PMID: 32324313 Free PMC article.
Physiologically-Based Pharmacokinetic Modeling Characterizes the CYP3A-Mediated Drug-Drug Interaction Between Fluconazole and Sildenafil in Infants.
Salerno SN, Edginton A, Gerhart JG, Laughon MM, Ambalavanan N, Sokol GM, Hornik CD, Stewart D, Mills M, Martz K, Gonzalez D; Pharmaceuticals for Children Act - Pediatric Trials Network Steering Committee. Salerno SN, et al. Clin Pharmacol Ther. 2021 Jan;109(1):253-262. doi: 10.1002/cpt.1990. Epub 2020 Aug 22. Clin Pharmacol Ther. 2021. PMID: 32691891 Free PMC article.
Simultaneous determination of trimethoprim and sulfamethoxazole in dried plasma and urine spots.
Gonzalez D, Melloni C, Poindexter BB, Yogev R, Atz AM, Sullivan JE, Mendley SR, Delmore P, Delinsky A, Zimmerman K, Lewandowski A, Harper B, Lewis KC, Benjamin DK Jr, Cohen-Wolkowiez M; Best Pharmaceuticals for Children Act--Pediatric Trials Network Administrative Core Committee. Gonzalez D, et al. Among authors: delmore p. Bioanalysis. 2015;7(9):1137-49. doi: 10.4155/bio.15.38. Bioanalysis. 2015. PMID: 26039810 Free PMC article.
Use of physiologically-based pharmacokinetic modeling to inform dosing of the opioid analgesics fentanyl and methadone in children with obesity.
Gerhart JG, Carreño FO, Ford JL, Edginton AN, Perrin EM, Watt KM, Muller WJ, Atz AM, Al-Uzri A, Delmore P, Gonzalez D; Best Pharmaceuticals for Children Act-Pediatric Trials Network Steering Committee. Gerhart JG, et al. Among authors: delmore p. CPT Pharmacometrics Syst Pharmacol. 2022 Jun;11(6):778-791. doi: 10.1002/psp4.12793. Epub 2022 May 2. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 35491971 Free PMC article.
Comparative Analysis of Ampicillin Plasma and Dried Blood Spot Pharmacokinetics in Neonates.
Le J, Poindexter B, Sullivan JE, Laughon M, Delmore P, Blackford M, Yogev R, James LP, Melloni C, Harper B, Mitchell J, Benjamin DK Jr, Boakye-Agyeman F, Cohen-Wolkowiez M. Le J, et al. Among authors: delmore p. Ther Drug Monit. 2018 Feb;40(1):103-108. doi: 10.1097/FTD.0000000000000466. Ther Drug Monit. 2018. PMID: 29271816 Free PMC article.
55 results