Hill PJ - Search Results

1

Optimization of pyrrolamide topoisomerase II inhibitors toward identification of an antibacterial clinical candidate (AZD5099).

Basarab GS, Hill PJ, Garner CE, Hull K, Green O, Sherer BA, Dangel PB, Manchester JI, Bist S, Hauck S, Zhou F, Uria-Nickelsen M, Illingworth R, Alm R, Rooney M, Eakin AE. Basarab GS, et al. Among authors: hill pj. J Med Chem. 2014 Jul 24;57(14):6060-82. doi: 10.1021/jm500462x. Epub 2014 Jul 8. J Med Chem. 2014. PMID: 24959892

2

Pyrrolamide DNA gyrase inhibitors: optimization of antibacterial activity and efficacy.

Sherer BA, Hull K, Green O, Basarab G, Hauck S, Hill P, Loch JT 3rd, Mullen G, Bist S, Bryant J, Boriack-Sjodin A, Read J, DeGrace N, Uria-Nickelsen M, Illingworth RN, Eakin AE. Sherer BA, et al. Bioorg Med Chem Lett. 2011 Dec 15;21(24):7416-20. doi: 10.1016/j.bmcl.2011.10.010. Epub 2011 Oct 12. Bioorg Med Chem Lett. 2011. PMID: 22041057

3

Design of inhibitors of Helicobacter pylori glutamate racemase as selective antibacterial agents: incorporation of imidazoles onto a core pyrazolopyrimidinedione scaffold to improve bioavailabilty.

Basarab GS, Hill P, Eyermann CJ, Gowravaram M, Käck H, Osimoni E. Basarab GS, et al. Bioorg Med Chem Lett. 2012 Sep 1;22(17):5600-7. doi: 10.1016/j.bmcl.2012.07.004. Epub 2012 Jul 20. Bioorg Med Chem Lett. 2012. PMID: 22877632

4

Design of Helicobacter pylori glutamate racemase inhibitors as selective antibacterial agents: a novel pro-drug approach to increase exposure.

Basarab GS, Hill PJ, Rastagar A, Webborn PJ. Basarab GS, et al. Among authors: hill pj. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4716-22. doi: 10.1016/j.bmcl.2008.06.092. Epub 2008 Jul 2. Bioorg Med Chem Lett. 2008. PMID: 18640833

5

Exploring the UDP pocket of LpxC through amino acid analogs.

Hale MR, Hill P, Lahiri S, Miller MD, Ross P, Alm R, Gao N, Kutschke A, Johnstone M, Prince B, Thresher J, Yang W. Hale MR, et al. Bioorg Med Chem Lett. 2013 Apr 15;23(8):2362-7. doi: 10.1016/j.bmcl.2013.02.055. Epub 2013 Mar 1. Bioorg Med Chem Lett. 2013. PMID: 23499237

6

Potent and selective inhibitors of Helicobacter pylori glutamate racemase (MurI): pyridodiazepine amines.

Geng B, Basarab G, Comita-Prevoir J, Gowravaram M, Hill P, Kiely A, Loch J, MacPherson L, Morningstar M, Mullen G, Osimboni E, Satz A, Eyermann C, Lundqvist T. Geng B, et al. Bioorg Med Chem Lett. 2009 Feb 1;19(3):930-6. doi: 10.1016/j.bmcl.2008.11.113. Epub 2008 Dec 6. Bioorg Med Chem Lett. 2009. PMID: 19097892

7

Selective inhibitors of bacterial t-RNA-(N(1)G37) methyltransferase (TrmD) that demonstrate novel ordering of the lid domain.

Hill PJ, Abibi A, Albert R, Andrews B, Gagnon MM, Gao N, Grebe T, Hajec LI, Huang J, Livchak S, Lahiri SD, McKinney DC, Thresher J, Wang H, Olivier N, Buurman ET. Hill PJ, et al. J Med Chem. 2013 Sep 26;56(18):7278-88. doi: 10.1021/jm400718n. Epub 2013 Sep 17. J Med Chem. 2013. PMID: 23981144

8

Characterization of novel respiratory syncytial virus inhibitors identified by high throughput screen.

Laganas VA, Dunn EF, McLaughlin RE, Tiong-Yip CL, Yuzhakov O, Isabella VM, Hill P, Yu Q. Laganas VA, et al. Antiviral Res. 2015 Mar;115:71-4. doi: 10.1016/j.antiviral.2014.12.012. Epub 2014 Dec 24. Antiviral Res. 2015. PMID: 25542974

9

Overexpression of Pseudomonas aeruginosa LpxC with its inhibitors in an acrB-deficient Escherichia coli strain.

Gao N, McLeod SM, Hajec L, Olivier NB, Lahiri SD, Bryan Prince D, Thresher J, Ross PL, Whiteaker JD, Doig P, Li AH, Hill PJ, Cornebise M, Reck F, Hale MR. Gao N, et al. Among authors: hill pj. Protein Expr Purif. 2014 Dec;104:57-64. doi: 10.1016/j.pep.2014.09.006. Epub 2014 Sep 18. Protein Expr Purif. 2014. PMID: 25240855

10

Disruption of nontuberculous mycobacteria biofilms induces a highly vulnerable to antibiotic killing phenotype.

Kurbatfinski N, Hill PJ, Tobin N, Kramer CN, Wickham J, Goodman SD, Hall-Stoodley L, Bakaletz LO. Kurbatfinski N, et al. Among authors: hill pj. Biofilm. 2023 Nov 25;6:100166. doi: 10.1016/j.bioflm.2023.100166. eCollection 2023 Dec 15. Biofilm. 2023. PMID: 38078059 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

101 results

Search Page