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Epigenetic regulation of adult neural stem cells: implications for Alzheimer's disease.
Fitzsimons CP, van Bodegraven E, Schouten M, Lardenoije R, Kompotis K, Kenis G, van den Hurk M, Boks MP, Biojone C, Joca S, Steinbusch HW, Lunnon K, Mastroeni DF, Mill J, Lucassen PJ, Coleman PD, van den Hove DL, Rutten BP. Fitzsimons CP, et al. Among authors: van den hurk m, van bodegraven e, van den hove dl. Mol Neurodegener. 2014 Jun 25;9:25. doi: 10.1186/1750-1326-9-25. Mol Neurodegener. 2014. PMID: 24964731 Free PMC article. Review.
Transcriptome and proteome profiling of neural stem cells from the human subventricular zone in Parkinson's disease.
Donega V, Burm SM, van Strien ME, van Bodegraven EJ, Paliukhovich I, Geut H, van de Berg WDJ, Li KW, Smit AB, Basak O, Hol EM. Donega V, et al. Among authors: van de berg wdj, van strien me, van bodegraven ej. Acta Neuropathol Commun. 2019 Jun 3;7(1):84. doi: 10.1186/s40478-019-0736-0. Acta Neuropathol Commun. 2019. PMID: 31159890 Free PMC article.
Histone acetylation in astrocytes suppresses GFAP and stimulates a reorganization of the intermediate filament network.
Kanski R, Sneeboer MA, van Bodegraven EJ, Sluijs JA, Kropff W, Vermunt MW, Creyghton MP, De Filippis L, Vescovi A, Aronica E, van Tijn P, van Strien ME, Hol EM. Kanski R, et al. Among authors: van bodegraven ej, van strien me, van tijn p. J Cell Sci. 2014 Oct 15;127(Pt 20):4368-80. doi: 10.1242/jcs.145912. Epub 2014 Aug 15. J Cell Sci. 2014. PMID: 25128567
Microglia innately develop within cerebral organoids.
Ormel PR, Vieira de Sá R, van Bodegraven EJ, Karst H, Harschnitz O, Sneeboer MAM, Johansen LE, van Dijk RE, Scheefhals N, Berdenis van Berlekom A, Ribes Martínez E, Kling S, MacGillavry HD, van den Berg LH, Kahn RS, Hol EM, de Witte LD, Pasterkamp RJ. Ormel PR, et al. Among authors: van bodegraven ej, van den berg lh, van dijk re. Nat Commun. 2018 Oct 9;9(1):4167. doi: 10.1038/s41467-018-06684-2. Nat Commun. 2018. PMID: 30301888 Free PMC article.
Adverse prognosis of glioblastoma contacting the subventricular zone: Biological correlates.
Berendsen S, van Bodegraven E, Seute T, Spliet WGM, Geurts M, Hendrikse J, Schoysman L, Huiszoon WB, Varkila M, Rouss S, Bell EH, Kroonen J, Chakravarti A, Bours V, Snijders TJ, Robe PA. Berendsen S, et al. Among authors: van bodegraven e. PLoS One. 2019 Oct 11;14(10):e0222717. doi: 10.1371/journal.pone.0222717. eCollection 2019. PLoS One. 2019. PMID: 31603915 Free PMC article.
GFAPδ/GFAPα ratio directs astrocytoma gene expression towards a more malignant profile.
Stassen OMJA, van Bodegraven EJ, Giuliani F, Moeton M, Kanski R, Sluijs JA, van Strien ME, Kamphuis W, Robe PAJ, Hol EM. Stassen OMJA, et al. Among authors: van bodegraven ej, van strien me. Oncotarget. 2017 Oct 4;8(50):88104-88121. doi: 10.18632/oncotarget.21540. eCollection 2017 Oct 20. Oncotarget. 2017. PMID: 29152145 Free PMC article.
GFAP alternative splicing regulates glioma cell-ECM interaction in a DUSP4-dependent manner.
van Bodegraven EJ, van Asperen JV, Sluijs JA, van Deursen CBJ, van Strien ME, Stassen OMJA, Robe PAJ, Hol EM. van Bodegraven EJ, et al. Among authors: van deursen cbj, van asperen jv, van strien me. FASEB J. 2019 Nov;33(11):12941-12959. doi: 10.1096/fj.201900916R. Epub 2019 Aug 31. FASEB J. 2019. PMID: 31480854
This study supports the hypothesis that glioma cells with a high GFAP-delta/alpha ratio are highly invasive and more malignant cells, thus making GFAP alternative splicing a potential therapeutic target.-Van Bodegraven, E. J., van Asperen, J. V., Sluij …
This study supports the hypothesis that glioma cells with a high GFAP-delta/alpha ratio are highly invasive and more malignant cells, thus m …
39 results