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Ear2 deletion causes early memory and learning deficits in APP/PS1 mice.
Kummer MP, Hammerschmidt T, Martinez A, Terwel D, Eichele G, Witten A, Figura S, Stoll M, Schwartz S, Pape HC, Schultze JL, Weinshenker D, Heneka MT, Urban I. Kummer MP, et al. Among authors: eichele g. J Neurosci. 2014 Jun 25;34(26):8845-54. doi: 10.1523/JNEUROSCI.4027-13.2014. J Neurosci. 2014. PMID: 24966384 Free PMC article.
TIP60/KAT5 is required for neuronal viability in hippocampal CA1.
Urban I, Kerimoglu C, Sakib MS, Wang H, Benito E, Thaller C, Zhou X, Yan J, Fischer A, Eichele G. Urban I, et al. Among authors: eichele g. Sci Rep. 2019 Nov 7;9(1):16173. doi: 10.1038/s41598-019-50927-1. Sci Rep. 2019. PMID: 31700011 Free PMC article.
Web-based digital gene expression atlases for the mouse.
Geffers L, Herrmann B, Eichele G. Geffers L, et al. Among authors: eichele g. Mamm Genome. 2012 Oct;23(9-10):525-38. doi: 10.1007/s00335-012-9413-3. Epub 2012 Aug 31. Mamm Genome. 2012. PMID: 22936000 Review.
Postnatal expression of the lysine methyltransferase SETD1B is essential for learning and the regulation of neuron-enriched genes.
Michurina A, Sakib MS, Kerimoglu C, Krüger DM, Kaurani L, Islam MR, Joshi PD, Schröder S, Centeno TP, Zhou J, Pradhan R, Cha J, Xu X, Eichele G, Zeisberg EM, Kranz A, Stewart AF, Fischer A. Michurina A, et al. Among authors: eichele g. EMBO J. 2022 Jan 4;41(1):e106459. doi: 10.15252/embj.2020106459. Epub 2021 Nov 22. EMBO J. 2022. PMID: 34806773 Free PMC article.
The diphenylpyrazole compound anle138b blocks Aβ channels and rescues disease phenotypes in a mouse model for amyloid pathology.
Martinez Hernandez A, Urbanke H, Gillman AL, Lee J, Ryazanov S, Agbemenyah HY, Benito E, Jain G, Kaurani L, Grigorian G, Leonov A, Rezaei-Ghaleh N, Wilken P, Arce FT, Wagner J, Fuhrmann M, Caruana M, Camilleri A, Vassallo N, Zweckstetter M, Benz R, Giese A, Schneider A, Korte M, Lal R, Griesinger C, Eichele G, Fischer A. Martinez Hernandez A, et al. Among authors: eichele g. EMBO Mol Med. 2018 Jan;10(1):32-47. doi: 10.15252/emmm.201707825. EMBO Mol Med. 2018. PMID: 29208638 Free PMC article.
150 results