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Page 1
A phase 1 study investigating DX-2930 in healthy subjects.
Chyung Y, Vince B, Iarrobino R, Sexton D, Kenniston J, Faucette R, TenHoor C, Stolz LE, Stevens C, Biedenkapp J, Adelman B. Chyung Y, et al. Among authors: kenniston j. Ann Allergy Asthma Immunol. 2014 Oct;113(4):460-6.e2. doi: 10.1016/j.anai.2014.05.028. Epub 2014 Jun 26. Ann Allergy Asthma Immunol. 2014. PMID: 24980392 Free article. Clinical Trial.
Inhibiting Plasma Kallikrein for Hereditary Angioedema Prophylaxis.
Banerji A, Busse P, Shennak M, Lumry W, Davis-Lorton M, Wedner HJ, Jacobs J, Baker J, Bernstein JA, Lockey R, Li HH, Craig T, Cicardi M, Riedl M, Al-Ghazawi A, Soo C, Iarrobino R, Sexton DJ, TenHoor C, Kenniston JA, Faucette R, Still JG, Kushner H, Mensah R, Stevens C, Biedenkapp JC, Chyung Y, Adelman B. Banerji A, et al. Among authors: kenniston ja. N Engl J Med. 2017 Feb 23;376(8):717-728. doi: 10.1056/NEJMoa1605767. N Engl J Med. 2017. PMID: 28225674 Free article. Clinical Trial.
Inhibition of plasma kallikrein by a highly specific active site blocking antibody.
Kenniston JA, Faucette RR, Martik D, Comeau SR, Lindberg AP, Kopacz KJ, Conley GP, Chen J, Viswanathan M, Kastrapeli N, Cosic J, Mason S, DiLeo M, Abendroth J, Kuzmic P, Ladner RC, Edwards TE, TenHoor C, Adelman BA, Nixon AE, Sexton DJ. Kenniston JA, et al. J Biol Chem. 2014 Aug 22;289(34):23596-608. doi: 10.1074/jbc.M114.569061. Epub 2014 Jun 26. J Biol Chem. 2014. PMID: 24970892 Free PMC article.
Sculpting the proteome with AAA(+) proteases and disassembly machines.
Sauer RT, Bolon DN, Burton BM, Burton RE, Flynn JM, Grant RA, Hersch GL, Joshi SA, Kenniston JA, Levchenko I, Neher SB, Oakes ES, Siddiqui SM, Wah DA, Baker TA. Sauer RT, et al. Cell. 2004 Oct 1;119(1):9-18. doi: 10.1016/j.cell.2004.09.020. Cell. 2004. PMID: 15454077 Free PMC article. Review.
Signaling degradation.
Kenniston JA, Sauer RT. Kenniston JA, et al. Nat Struct Mol Biol. 2004 Sep;11(9):800-2. doi: 10.1038/nsmb0904-800. Nat Struct Mol Biol. 2004. PMID: 15332074 No abstract available.
18 results