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Suv39h-dependent H3K9me3 marks intact retrotransposons and silences LINE elements in mouse embryonic stem cells.
Bulut-Karslioglu A, De La Rosa-Velázquez IA, Ramirez F, Barenboim M, Onishi-Seebacher M, Arand J, Galán C, Winter GE, Engist B, Gerle B, O'Sullivan RJ, Martens JH, Walter J, Manke T, Lachner M, Jenuwein T. Bulut-Karslioglu A, et al. Among authors: galan c. Mol Cell. 2014 Jul 17;55(2):277-90. doi: 10.1016/j.molcel.2014.05.029. Epub 2014 Jun 26. Mol Cell. 2014. PMID: 24981170 Free article.
Major satellite repeat RNA stabilize heterochromatin retention of Suv39h enzymes by RNA-nucleosome association and RNA:DNA hybrid formation.
Velazquez Camacho O, Galan C, Swist-Rosowska K, Ching R, Gamalinda M, Karabiber F, De La Rosa-Velazquez I, Engist B, Koschorz B, Shukeir N, Onishi-Seebacher M, van de Nobelen S, Jenuwein T. Velazquez Camacho O, et al. Among authors: galan c. Elife. 2017 Aug 1;6:e25293. doi: 10.7554/eLife.25293. Elife. 2017. PMID: 28760199 Free PMC article.
Heterochromatin establishment during early mammalian development is regulated by pericentromeric RNA and characterized by non-repressive H3K9me3.
Burton A, Brochard V, Galan C, Ruiz-Morales ER, Rovira Q, Rodriguez-Terrones D, Kruse K, Le Gras S, Udayakumar VS, Chin HG, Eid A, Liu X, Wang C, Gao S, Pradhan S, Vaquerizas JM, Beaujean N, Jenuwein T, Torres-Padilla ME. Burton A, et al. Among authors: galan c. Nat Cell Biol. 2020 Jul;22(7):767-778. doi: 10.1038/s41556-020-0536-6. Epub 2020 Jun 29. Nat Cell Biol. 2020. PMID: 32601371 Free PMC article.
227 results