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TCF7L2 is a master regulator of insulin production and processing.
Zhou Y, Park SY, Su J, Bailey K, Ottosson-Laakso E, Shcherbina L, Oskolkov N, Zhang E, Thevenin T, Fadista J, Bennet H, Vikman P, Wierup N, Fex M, Rung J, Wollheim C, Nobrega M, Renström E, Groop L, Hansson O. Zhou Y, et al. Among authors: nobrega m. Hum Mol Genet. 2014 Dec 15;23(24):6419-31. doi: 10.1093/hmg/ddu359. Epub 2014 Jul 11. Hum Mol Genet. 2014. PMID: 25015099 Free PMC article.
In vitro scan for enhancers at the TCF7L2 locus.
Savic D, Park SY, Bailey KA, Bell GI, Nobrega MA. Savic D, et al. Among authors: nobrega ma. Diabetologia. 2013 Jan;56(1):121-5. doi: 10.1007/s00125-012-2730-y. Epub 2012 Sep 26. Diabetologia. 2013. PMID: 23011354 Free PMC article.
Modulation ofTcf7l2 expression alters behavior in mice.
Savic D, Distler MG, Sokoloff G, Shanahan NA, Dulawa SC, Palmer AA, Nobrega MA. Savic D, et al. PLoS One. 2011;6(10):e26897. doi: 10.1371/journal.pone.0026897. Epub 2011 Oct 27. PLoS One. 2011. PMID: 22046400 Free PMC article.
DNA methylation in lung cells is associated with asthma endotypes and genetic risk.
Nicodemus-Johnson J, Myers RA, Sakabe NJ, Sobreira DR, Hogarth DK, Naureckas ET, Sperling AI, Solway J, White SR, Nobrega MA, Nicolae DL, Gilad Y, Ober C. Nicodemus-Johnson J, et al. JCI Insight. 2016 Dec 8;1(20):e90151. doi: 10.1172/jci.insight.90151. JCI Insight. 2016. PMID: 27942592 Free PMC article.
A promoter interaction map for cardiovascular disease genetics.
Montefiori LE, Sobreira DR, Sakabe NJ, Aneas I, Joslin AC, Hansen GT, Bozek G, Moskowitz IP, McNally EM, Nóbrega MA. Montefiori LE, et al. Among authors: nobrega ma. Elife. 2018 Jul 10;7:e35788. doi: 10.7554/eLife.35788. Elife. 2018. PMID: 29988018 Free PMC article.
362 results