Friedman N - Search Results

1

T-cell receptor repertoires share a restricted set of public and abundant CDR3 sequences that are associated with self-related immunity.

Madi A, Shifrut E, Reich-Zeliger S, Gal H, Best K, Ndifon W, Chain B, Cohen IR, Friedman N. Madi A, et al. Among authors: friedman n. Genome Res. 2014 Oct;24(10):1603-12. doi: 10.1101/gr.170753.113. Epub 2014 Jul 14. Genome Res. 2014. PMID: 25024161 Free PMC article.

2

Chromatin conformation governs T-cell receptor Jβ gene segment usage.

Ndifon W, Gal H, Shifrut E, Aharoni R, Yissachar N, Waysbort N, Reich-Zeliger S, Arnon R, Friedman N. Ndifon W, et al. Among authors: friedman n. Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):15865-70. doi: 10.1073/pnas.1203916109. Epub 2012 Sep 10. Proc Natl Acad Sci U S A. 2012. PMID: 22984176 Free PMC article.

3

Tracking global changes induced in the CD4 T-cell receptor repertoire by immunization with a complex antigen using short stretches of CDR3 protein sequence.

Thomas N, Best K, Cinelli M, Reich-Zeliger S, Gal H, Shifrut E, Madi A, Friedman N, Shawe-Taylor J, Chain B. Thomas N, et al. Among authors: friedman n. Bioinformatics. 2014 Nov 15;30(22):3181-8. doi: 10.1093/bioinformatics/btu523. Epub 2014 Aug 5. Bioinformatics. 2014. PMID: 25095879 Free PMC article.

4

Feature selection using a one dimensional naïve Bayes' classifier increases the accuracy of support vector machine classification of CDR3 repertoires.

Cinelli M, Sun Y, Best K, Heather JM, Reich-Zeliger S, Shifrut E, Friedman N, Shawe-Taylor J, Chain B. Cinelli M, et al. Among authors: friedman n. Bioinformatics. 2017 Apr 1;33(7):951-955. doi: 10.1093/bioinformatics/btw771. Bioinformatics. 2017. PMID: 28073756 Free PMC article.

5

T cell receptor repertoires of mice and humans are clustered in similarity networks around conserved public CDR3 sequences.

Madi A, Poran A, Shifrut E, Reich-Zeliger S, Greenstein E, Zaretsky I, Arnon T, Laethem FV, Singer A, Lu J, Sun PD, Cohen IR, Friedman N. Madi A, et al. Among authors: friedman n. Elife. 2017 Jul 21;6:e22057. doi: 10.7554/eLife.22057. Elife. 2017. PMID: 28731407 Free PMC article.

6

Coupled IL-2-dependent extracellular feedbacks govern two distinct consecutive phases of CD4 T cell activation.

Waysbort N, Russ D, Chain BM, Friedman N. Waysbort N, et al. Among authors: friedman n. J Immunol. 2013 Dec 15;191(12):5822-30. doi: 10.4049/jimmunol.1301575. Epub 2013 Nov 15. J Immunol. 2013. PMID: 24244020

7

CD4(+) T Cell-Receptor Repertoire Diversity is Compromised in the Spleen but Not in the Bone Marrow of Aged Mice Due to Private and Sporadic Clonal Expansions.

Shifrut E, Baruch K, Gal H, Ndifon W, Deczkowska A, Schwartz M, Friedman N. Shifrut E, et al. Among authors: friedman n. Front Immunol. 2013 Nov 19;4:379. doi: 10.3389/fimmu.2013.00379. eCollection 2013. Front Immunol. 2013. PMID: 24312094 Free PMC article.

8

Specificity, Privacy, and Degeneracy in the CD4 T Cell Receptor Repertoire Following Immunization.

Sun Y, Best K, Cinelli M, Heather JM, Reich-Zeliger S, Shifrut E, Friedman N, Shawe-Taylor J, Chain B. Sun Y, et al. Among authors: friedman n. Front Immunol. 2017 Apr 13;8:430. doi: 10.3389/fimmu.2017.00430. eCollection 2017. Front Immunol. 2017. PMID: 28450864 Free PMC article.

9

McPAS-TCR: a manually curated catalogue of pathology-associated T cell receptor sequences.

Tickotsky N, Sagiv T, Prilusky J, Shifrut E, Friedman N. Tickotsky N, et al. Among authors: friedman n. Bioinformatics. 2017 Sep 15;33(18):2924-2929. doi: 10.1093/bioinformatics/btx286. Bioinformatics. 2017. PMID: 28481982

10

A hierarchy of selection pressures determines the organization of the T cell receptor repertoire.

Mark M, Reich-Zeliger S, Greenstein E, Reshef D, Madi A, Chain B, Friedman N. Mark M, et al. Among authors: friedman n. Front Immunol. 2022 Jul 29;13:939394. doi: 10.3389/fimmu.2022.939394. eCollection 2022. Front Immunol. 2022. PMID: 35967295 Free PMC article.

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