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Aerosol vaccination with AERAS-402 elicits robust cellular immune responses in the lungs of rhesus macaques but fails to protect against high-dose Mycobacterium tuberculosis challenge.
Darrah PA, Bolton DL, Lackner AA, Kaushal D, Aye PP, Mehra S, Blanchard JL, Didier PJ, Roy CJ, Rao SS, Hokey DA, Scanga CA, Sizemore DR, Sadoff JC, Roederer M, Seder RA. Darrah PA, et al. J Immunol. 2014 Aug 15;193(4):1799-811. doi: 10.4049/jimmunol.1400676. Epub 2014 Jul 14. J Immunol. 2014. PMID: 25024382 Free PMC article.
Innate immune responses to Rhodococcus equi.
Darrah PA, Monaco MC, Jain S, Hondalus MK, Golenbock DT, Mosser DM. Darrah PA, et al. J Immunol. 2004 Aug 1;173(3):1914-24. doi: 10.4049/jimmunol.173.3.1914. J Immunol. 2004. PMID: 15265925
CD8+ T cell responses following replication-defective adenovirus serotype 5 immunization are dependent on CD11c+ dendritic cells but show redundancy in their requirement of TLR and nucleotide-binding oligomerization domain-like receptor signaling.
Lindsay RW, Darrah PA, Quinn KM, Wille-Reece U, Mattei LM, Iwasaki A, Kasturi SP, Pulendran B, Gall JG, Spies AG, Seder RA. Lindsay RW, et al. Among authors: darrah pa. J Immunol. 2010 Aug 1;185(3):1513-21. doi: 10.4049/jimmunol.1000338. Epub 2010 Jul 7. J Immunol. 2010. PMID: 20610651
The regulation of Th1 responses by the p38 MAPK.
Yang Z, Zhang X, Darrah PA, Mosser DM. Yang Z, et al. Among authors: darrah pa. J Immunol. 2010 Nov 15;185(10):6205-13. doi: 10.4049/jimmunol.1000243. Epub 2010 Oct 11. J Immunol. 2010. PMID: 20937847 Free PMC article.
45 results