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The glutathione biosynthetic pathway of Plasmodium is essential for mosquito transmission.
Vega-Rodríguez J, Franke-Fayard B, Dinglasan RR, Janse CJ, Pastrana-Mena R, Waters AP, Coppens I, Rodríguez-Orengo JF, Srinivasan P, Jacobs-Lorena M, Serrano AE. Vega-Rodríguez J, et al. Among authors: dinglasan rr. PLoS Pathog. 2009 Feb;5(2):e1000302. doi: 10.1371/journal.ppat.1000302. Epub 2009 Feb 20. PLoS Pathog. 2009. PMID: 19229315 Free PMC article.
Glutathione reductase-null malaria parasites have normal blood stage growth but arrest during development in the mosquito.
Pastrana-Mena R, Dinglasan RR, Franke-Fayard B, Vega-Rodríguez J, Fuentes-Caraballo M, Baerga-Ortiz A, Coppens I, Jacobs-Lorena M, Janse CJ, Serrano AE. Pastrana-Mena R, et al. Among authors: dinglasan rr. J Biol Chem. 2010 Aug 27;285(35):27045-27056. doi: 10.1074/jbc.M110.122275. Epub 2010 Jun 23. J Biol Chem. 2010. PMID: 20573956 Free PMC article.
Expression, immunogenicity, histopathology, and potency of a mosquito-based malaria transmission-blocking recombinant vaccine.
Mathias DK, Plieskatt JL, Armistead JS, Bethony JM, Abdul-Majid KB, McMillan A, Angov E, Aryee MJ, Zhan B, Gillespie P, Keegan B, Jariwala AR, Rezende W, Bottazzi ME, Scorpio DG, Hotez PJ, Dinglasan RR. Mathias DK, et al. Among authors: dinglasan rr. Infect Immun. 2012 Apr;80(4):1606-14. doi: 10.1128/IAI.06212-11. Epub 2012 Feb 6. Infect Immun. 2012. PMID: 22311924 Free PMC article.
Structural characterization and inhibition of the Plasmodium Atg8-Atg3 interaction.
Hain AU, Weltzer RR, Hammond H, Jayabalasingham B, Dinglasan RR, Graham DR, Colquhoun DR, Coppens I, Bosch J. Hain AU, et al. Among authors: dinglasan rr. J Struct Biol. 2012 Dec;180(3):551-62. doi: 10.1016/j.jsb.2012.09.001. Epub 2012 Sep 13. J Struct Biol. 2012. PMID: 22982544 Free PMC article.
A bioinformatics approach for integrated transcriptomic and proteomic comparative analyses of model and non-sequenced anopheline vectors of human malaria parasites.
Ubaida Mohien C, Colquhoun DR, Mathias DK, Gibbons JG, Armistead JS, Rodriguez MC, Rodriguez MH, Edwards NJ, Hartler J, Thallinger GG, Graham DR, Martinez-Barnetche J, Rokas A, Dinglasan RR. Ubaida Mohien C, et al. Among authors: dinglasan rr. Mol Cell Proteomics. 2013 Jan;12(1):120-31. doi: 10.1074/mcp.M112.019596. Epub 2012 Oct 17. Mol Cell Proteomics. 2013. PMID: 23082028 Free PMC article.
94 results