Rathinam VAK - Search Results

1

Caspase-8 modulates dectin-1 and complement receptor 3-driven IL-1β production in response to β-glucans and the fungal pathogen, Candida albicans.

Ganesan S, Rathinam VAK, Bossaller L, Army K, Kaiser WJ, Mocarski ES, Dillon CP, Green DR, Mayadas TN, Levitz SM, Hise AG, Silverman N, Fitzgerald KA. Ganesan S, et al. Among authors: rathinam vak. J Immunol. 2014 Sep 1;193(5):2519-2530. doi: 10.4049/jimmunol.1400276. Epub 2014 Jul 25. J Immunol. 2014. PMID: 25063877 Free PMC article.

2

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses.

Rathinam VA, Jiang Z, Waggoner SN, Sharma S, Cole LE, Waggoner L, Vanaja SK, Monks BG, Ganesan S, Latz E, Hornung V, Vogel SN, Szomolanyi-Tsuda E, Fitzgerald KA. Rathinam VA, et al. Nat Immunol. 2010 May;11(5):395-402. doi: 10.1038/ni.1864. Epub 2010 Mar 28. Nat Immunol. 2010. PMID: 20351692 Free PMC article.

3

Catenin' on to nucleic acid sensing.

Rathinam VA, Sharma S, Fitzgerald KA. Rathinam VA, et al. Nat Immunol. 2010 Jun;11(6):466-8. doi: 10.1038/ni0610-466. Nat Immunol. 2010. PMID: 20485273 No abstract available.

4

Inflammasomes and anti-viral immunity.

Rathinam VA, Fitzgerald KA. Rathinam VA, et al. J Clin Immunol. 2010 Sep;30(5):632-7. doi: 10.1007/s10875-010-9431-4. Epub 2010 Jul 28. J Clin Immunol. 2010. PMID: 20665097 Review.

5

Aim2 deficiency stimulates the expression of IFN-inducible Ifi202, a lupus susceptibility murine gene within the Nba2 autoimmune susceptibility locus.

Panchanathan R, Duan X, Shen H, Rathinam VA, Erickson LD, Fitzgerald KA, Choubey D. Panchanathan R, et al. J Immunol. 2010 Dec 15;185(12):7385-93. doi: 10.4049/jimmunol.1002468. Epub 2010 Nov 5. J Immunol. 2010. PMID: 21057088 Free PMC article.

6

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome.

Nakahira K, Haspel JA, Rathinam VA, Lee SJ, Dolinay T, Lam HC, Englert JA, Rabinovitch M, Cernadas M, Kim HP, Fitzgerald KA, Ryter SW, Choi AM. Nakahira K, et al. Nat Immunol. 2011 Mar;12(3):222-30. doi: 10.1038/ni.1980. Epub 2010 Dec 12. Nat Immunol. 2011. PMID: 21151103 Free PMC article.

7

Innate immune sensing of DNA viruses.

Rathinam VA, Fitzgerald KA. Rathinam VA, et al. Virology. 2011 Mar 15;411(2):153-62. doi: 10.1016/j.virol.2011.02.003. Epub 2011 Feb 18. Virology. 2011. PMID: 21334037 Free PMC article. Review.

8

Aim2 deficiency in mice suppresses the expression of the inhibitory Fcgamma receptor (FcgammaRIIB) through the induction of the IFN-inducible p202, a lupus susceptibility protein.

Panchanathan R, Shen H, Duan X, Rathinam VA, Erickson LD, Fitzgerald KA, Choubey D. Panchanathan R, et al. J Immunol. 2011 Jun 15;186(12):6762-70. doi: 10.4049/jimmunol.1003638. Epub 2011 May 6. J Immunol. 2011. PMID: 21551362 Free PMC article.

9

Chitosan but not chitin activates the inflammasome by a mechanism dependent upon phagocytosis.

Bueter CL, Lee CK, Rathinam VAK, Healy GJ, Taron CH, Specht CA, Levitz SM. Bueter CL, et al. Among authors: rathinam vak. J Biol Chem. 2011 Oct 14;286(41):35447-35455. doi: 10.1074/jbc.M111.274936. Epub 2011 Aug 23. J Biol Chem. 2011. PMID: 21862582 Free PMC article.

10

Regulation of inflammasome signaling.

Rathinam VA, Vanaja SK, Fitzgerald KA. Rathinam VA, et al. Nat Immunol. 2012 Mar 19;13(4):333-42. doi: 10.1038/ni.2237. Nat Immunol. 2012. PMID: 22430786 Free PMC article. Review.

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