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A novel MMP12 locus is associated with large artery atherosclerotic stroke using a genome-wide age-at-onset informed approach.
Traylor M, Mäkelä KM, Kilarski LL, Holliday EG, Devan WJ, Nalls MA, Wiggins KL, Zhao W, Cheng YC, Achterberg S, Malik R, Sudlow C, Bevan S, Raitoharju E; METASTROKE, International Stroke Genetics Consortium, Wellcome Trust Case Consortium 2 (WTCCC2); Oksala N, Thijs V, Lemmens R, Lindgren A, Slowik A, Maguire JM, Walters M, Algra A, Sharma P, Attia JR, Boncoraglio GB, Rothwell PM, de Bakker PI, Bis JC, Saleheen D, Kittner SJ, Mitchell BD, Rosand J, Meschia JF, Levi C, Dichgans M, Lehtimäki T, Lewis CM, Markus HS. Traylor M, et al. Among authors: oksala n. PLoS Genet. 2014 Jul 31;10(7):e1004469. doi: 10.1371/journal.pgen.1004469. eCollection 2014 Jul. PLoS Genet. 2014. PMID: 25078452 Free PMC article.
ADAM8 and its single nucleotide polymorphism 2662 T/G are associated with advanced atherosclerosis and fatal myocardial infarction: Tampere vascular study.
Levula M, Airla N, Oksala N, Hernesniemi JA, Pelto-Huikko M, Salenius JP, Zeitlin R, Järvinen O, Huovila AP, Nikkari ST, Jaakkola O, Ilveskoski E, Mikkelsson J, Perola M, Laaksonen R, Kytömäki L, Soini JT, Kähönen M, Parkkinen J, Karhunen PJ, Lehtimäki T. Levula M, et al. Among authors: oksala n. Ann Med. 2009;41(7):497-507. doi: 10.1080/07853890903025945. Ann Med. 2009. PMID: 19575316
Proprotein convertases in human atherosclerotic plaques: the overexpression of FURIN and its substrate cytokines BAFF and APRIL.
Turpeinen H, Raitoharju E, Oksanen A, Oksala N, Levula M, Lyytikäinen LP, Järvinen O, Creemers JW, Kähönen M, Laaksonen R, Pelto-Huikko M, Lehtimäki T, Pesu M. Turpeinen H, et al. Among authors: oksala n. Atherosclerosis. 2011 Dec;219(2):799-806. doi: 10.1016/j.atherosclerosis.2011.08.011. Epub 2011 Aug 22. Atherosclerosis. 2011. PMID: 21889147
Genetic profiling using genome-wide significant coronary artery disease risk variants does not improve the prediction of subclinical atherosclerosis: the Cardiovascular Risk in Young Finns Study, the Bogalusa Heart Study and the Health 2000 Survey--a meta-analysis of three independent studies.
Hernesniemi JA, Seppälä I, Lyytikäinen LP, Mononen N, Oksala N, Hutri-Kähönen N, Juonala M, Taittonen L, Smith EN, Schork NJ, Chen W, Srinivasan SR, Berenson GS, Murray SS, Laitinen T, Jula A, Kettunen J, Ripatti S, Laaksonen R, Viikari J, Kähönen M, Raitakari OT, Lehtimäki T. Hernesniemi JA, et al. Among authors: oksala n. PLoS One. 2012;7(1):e28931. doi: 10.1371/journal.pone.0028931. Epub 2012 Jan 25. PLoS One. 2012. PMID: 22295058 Free PMC article.
Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.
Inouye M, Ripatti S, Kettunen J, Lyytikäinen LP, Oksala N, Laurila PP, Kangas AJ, Soininen P, Savolainen MJ, Viikari J, Kähönen M, Perola M, Salomaa V, Raitakari O, Lehtimäki T, Taskinen MR, Järvelin MR, Ala-Korpela M, Palotie A, de Bakker PI. Inouye M, et al. Among authors: oksala n. PLoS Genet. 2012;8(8):e1002907. doi: 10.1371/journal.pgen.1002907. Epub 2012 Aug 16. PLoS Genet. 2012. PMID: 22916037 Free PMC article.
A comparison of the accuracy of Illumina HumanHT-12 v3 Expression BeadChip and TaqMan qRT-PCR gene expression results in patient samples from the Tampere Vascular Study.
Raitoharju E, Seppälä I, Lyytikäinen LP, Levula M, Oksala N, Klopp N, Illig T, Laaksonen R, Kähönen M, Lehtimäki T. Raitoharju E, et al. Among authors: oksala n. Atherosclerosis. 2013 Jan;226(1):149-52. doi: 10.1016/j.atherosclerosis.2012.10.078. Epub 2012 Nov 12. Atherosclerosis. 2013. PMID: 23177970
210 results