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p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression.
Moon SH, Huang CH, Houlihan SL, Regunath K, Freed-Pastor WA, Morris JP 4th, Tschaharganeh DF, Kastenhuber ER, Barsotti AM, Culp-Hill R, Xue W, Ho YJ, Baslan T, Li X, Mayle A, de Stanchina E, Zender L, Tong DR, D'Alessandro A, Lowe SW, Prives C. Moon SH, et al. Among authors: tschaharganeh df. Cell. 2019 Jan 24;176(3):564-580.e19. doi: 10.1016/j.cell.2018.11.011. Epub 2018 Dec 20. Cell. 2019. PMID: 30580964 Free PMC article.
Non-cell-autonomous tumor suppression by p53.
Lujambio A, Akkari L, Simon J, Grace D, Tschaharganeh DF, Bolden JE, Zhao Z, Thapar V, Joyce JA, Krizhanovsky V, Lowe SW. Lujambio A, et al. Among authors: tschaharganeh df. Cell. 2013 Apr 11;153(2):449-60. doi: 10.1016/j.cell.2013.03.020. Epub 2013 Apr 4. Cell. 2013. PMID: 23562644 Free PMC article.
Mutant p53 drives pancreatic cancer metastasis through cell-autonomous PDGF receptor β signaling.
Weissmueller S, Manchado E, Saborowski M, Morris JP 4th, Wagenblast E, Davis CA, Moon SH, Pfister NT, Tschaharganeh DF, Kitzing T, Aust D, Markert EK, Wu J, Grimmond SM, Pilarsky C, Prives C, Biankin AV, Lowe SW. Weissmueller S, et al. Among authors: tschaharganeh df. Cell. 2014 Apr 10;157(2):382-394. doi: 10.1016/j.cell.2014.01.066. Cell. 2014. PMID: 24725405 Free PMC article.
Coordinated Tumor Suppression by Chromosome 8p.
Tschaharganeh DF, Bosbach B, Lowe SW. Tschaharganeh DF, et al. Cancer Cell. 2016 May 9;29(5):617-619. doi: 10.1016/j.ccell.2016.04.011. Cancer Cell. 2016. PMID: 27165739 Free PMC article.
p53-Dependent Nestin Regulation Links Tumor Suppression to Cellular Plasticity in Liver Cancer.
Tschaharganeh DF, Xue W, Calvisi DF, Evert M, Michurina TV, Dow LE, Banito A, Katz SF, Kastenhuber ER, Weissmueller S, Huang CH, Lechel A, Andersen JB, Capper D, Zender L, Longerich T, Enikolopov G, Lowe SW. Tschaharganeh DF, et al. Cell. 2016 Jun 2;165(6):1546-1547. doi: 10.1016/j.cell.2016.05.058. Cell. 2016. PMID: 27259155 Free PMC article. No abstract available.
TNFα sensitizes hepatocytes to FasL-induced apoptosis by NFκB-mediated Fas upregulation.
Faletti L, Peintner L, Neumann S, Sandler S, Grabinger T, Mac Nelly S, Merfort I, Huang CH, Tschaharganeh D, Kang TW, Heinzmann F, D'Artista L, Maurer U, Brunner T, Lowe S, Zender L, Borner C. Faletti L, et al. Cell Death Dis. 2018 Sep 5;9(9):909. doi: 10.1038/s41419-018-0935-9. Cell Death Dis. 2018. PMID: 30185788 Free PMC article.
The SS18-SSX Oncoprotein Hijacks KDM2B-PRC1.1 to Drive Synovial Sarcoma.
Banito A, Li X, Laporte AN, Roe JS, Sanchez-Vega F, Huang CH, Dancsok AR, Hatzi K, Chen CC, Tschaharganeh DF, Chandwani R, Tasdemir N, Jones KB, Capecchi MR, Vakoc CR, Schultz N, Ladanyi M, Nielsen TO, Lowe SW. Banito A, et al. Among authors: tschaharganeh df. Cancer Cell. 2018 Mar 12;33(3):527-541.e8. doi: 10.1016/j.ccell.2018.01.018. Epub 2018 Mar 1. Cancer Cell. 2018. PMID: 29502955 Free PMC article.
Yes-associated protein up-regulates Jagged-1 and activates the Notch pathway in human hepatocellular carcinoma.
Tschaharganeh DF, Chen X, Latzko P, Malz M, Gaida MM, Felix K, Ladu S, Singer S, Pinna F, Gretz N, Sticht C, Tomasi ML, Delogu S, Evert M, Fan B, Ribback S, Jiang L, Brozzetti S, Bergmann F, Dombrowski F, Schirmacher P, Calvisi DF, Breuhahn K. Tschaharganeh DF, et al. Gastroenterology. 2013 Jun;144(7):1530-1542.e12. doi: 10.1053/j.gastro.2013.02.009. Epub 2013 Feb 16. Gastroenterology. 2013. PMID: 23419361 Free PMC article.
45 results