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Scribble is required for normal epithelial cell-cell contacts and lumen morphogenesis in the mammalian lung.
Yates LL, Schnatwinkel C, Hazelwood L, Chessum L, Paudyal A, Hilton H, Romero MR, Wilde J, Bogani D, Sanderson J, Formstone C, Murdoch JN, Niswander LA, Greenfield A, Dean CH. Yates LL, et al. Among authors: dean ch. Dev Biol. 2013 Jan 15;373(2):267-80. doi: 10.1016/j.ydbio.2012.11.012. Epub 2012 Nov 27. Dev Biol. 2013. PMID: 23195221 Free PMC article.
Pulmonary ORMDL3 is critical for induction of Alternaria-induced allergic airways disease.
Löser S, Gregory LG, Zhang Y, Schaefer K, Walker SA, Buckley J, Denney L, Dean CH, Cookson WOC, Moffatt MF, Lloyd CM. Löser S, et al. Among authors: dean ch. J Allergy Clin Immunol. 2017 May;139(5):1496-1507.e3. doi: 10.1016/j.jaci.2016.07.033. Epub 2016 Sep 10. J Allergy Clin Immunol. 2017. PMID: 27623174 Free PMC article.
Atmin mediates kidney morphogenesis by modulating Wnt signaling.
Goggolidou P, Hadjirin NF, Bak A, Papakrivopoulou E, Hilton H, Norris DP, Dean CH. Goggolidou P, et al. Hum Mol Genet. 2014 Oct 15;23(20):5303-16. doi: 10.1093/hmg/ddu246. Epub 2014 May 22. Hum Mol Genet. 2014. PMID: 24852369 Free PMC article.
The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear.
Paudyal A, Damrau C, Patterson VL, Ermakov A, Formstone C, Lalanne Z, Wells S, Lu X, Norris DP, Dean CH, Henderson DJ, Murdoch JN. Paudyal A, et al. Among authors: dean ch. BMC Dev Biol. 2010 Aug 12;10:87. doi: 10.1186/1471-213X-10-87. BMC Dev Biol. 2010. PMID: 20704721 Free PMC article.
Heterozygous Vangl2Looptail mice reveal novel roles for the planar cell polarity pathway in adult lung homeostasis and repair.
Poobalasingam T, Yates LL, Walker SA, Pereira M, Gross NY, Ali A, Kolatsi-Joannou M, Jarvelin MR, Pekkanen J, Papakrivopoulou E, Long DA, Griffiths M, Wagner D, Königshoff M, Hind M, Minelli C, Lloyd CM, Dean CH. Poobalasingam T, et al. Among authors: dean ch. Dis Model Mech. 2017 Apr 1;10(4):409-423. doi: 10.1242/dmm.028175. Epub 2017 Feb 24. Dis Model Mech. 2017. PMID: 28237967 Free PMC article.
1,448 results