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111 results

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Poly (ADP) ribose polymerase enzyme inhibitor, veliparib, potentiates chemotherapy and radiation in vitro and in vivo in small cell lung cancer.
Owonikoko TK, Zhang G, Deng X, Rossi MR, Switchenko JM, Doho GH, Chen Z, Kim S, Strychor S, Christner SM, Beumer J, Li C, Yue P, Chen A, Sica GL, Ramalingam SS, Kowalski J, Khuri FR, Sun SY. Owonikoko TK, et al. Among authors: sica gl. Cancer Med. 2014 Dec;3(6):1579-94. doi: 10.1002/cam4.317. Epub 2014 Aug 13. Cancer Med. 2014. PMID: 25124282 Free PMC article.
Novel small-molecule inhibitors of Bcl-XL to treat lung cancer.
Park D, Magis AT, Li R, Owonikoko TK, Sica GL, Sun SY, Ramalingam SS, Khuri FR, Curran WJ, Deng X. Park D, et al. Among authors: sica gl. Cancer Res. 2013 Sep 1;73(17):5485-96. doi: 10.1158/0008-5472.CAN-12-2272. Epub 2013 Jul 3. Cancer Res. 2013. PMID: 23824742 Free PMC article.
A Translational, Pharmacodynamic, and Pharmacokinetic Phase IB Clinical Study of Everolimus in Resectable Non-Small Cell Lung Cancer.
Owonikoko TK, Ramalingam SS, Miller DL, Force SD, Sica GL, Mendel J, Chen Z, Rogatko A, Tighiouart M, Harvey RD, Kim S, Saba NF, Pickens A, Behera M, Fu RW, Rossi MR, Auffermann WF, Torres WE, Bechara R, Deng X, Sun SY, Fu H, Gal AA, Khuri FR. Owonikoko TK, et al. Among authors: sica gl. Clin Cancer Res. 2015 Apr 15;21(8):1859-68. doi: 10.1158/1078-0432.CCR-14-1998. Epub 2015 Feb 11. Clin Cancer Res. 2015. PMID: 25673697 Free PMC article. Clinical Trial.
Small-Molecule Bcl2 BH4 Antagonist for Lung Cancer Therapy.
Han B, Park D, Li R, Xie M, Owonikoko TK, Zhang G, Sica GL, Ding C, Zhou J, Magis AT, Chen ZG, Shin DM, Ramalingam SS, Khuri FR, Curran WJ, Deng X. Han B, et al. Among authors: sica gl. Cancer Cell. 2015 Jun 8;27(6):852-63. doi: 10.1016/j.ccell.2015.04.010. Epub 2015 May 21. Cancer Cell. 2015. PMID: 26004684 Free PMC article.
Patient-derived xenografts faithfully replicated clinical outcome in a phase II co-clinical trial of arsenic trioxide in relapsed small cell lung cancer.
Owonikoko TK, Zhang G, Kim HS, Stinson RM, Bechara R, Zhang C, Chen Z, Saba NF, Pakkala S, Pillai R, Deng X, Sun SY, Rossi MR, Sica GL, Ramalingam SS, Khuri FR. Owonikoko TK, et al. Among authors: sica gl. J Transl Med. 2016 May 3;14(1):111. doi: 10.1186/s12967-016-0861-5. J Transl Med. 2016. PMID: 27142472 Free PMC article. Clinical Trial.
Small Molecule KRAS Agonist for Mutant KRAS Cancer Therapy.
Xu K, Park D, Magis AT, Zhang J, Zhou W, Sica GL, Ramalingam SS, Curran WJ, Deng X. Xu K, et al. Among authors: sica gl. Mol Cancer. 2019 Apr 10;18(1):85. doi: 10.1186/s12943-019-1012-4. Mol Cancer. 2019. PMID: 30971271 Free PMC article.
Mcl-1 Interacts with Akt to Promote Lung Cancer Progression.
Chen G, Park D, Magis AT, Behera M, Ramalingam SS, Owonikoko TK, Sica GL, Ye K, Zhang C, Chen Z, Curran WJ, Deng X. Chen G, et al. Among authors: sica gl. Cancer Res. 2019 Dec 15;79(24):6126-6138. doi: 10.1158/0008-5472.CAN-19-0950. Epub 2019 Oct 29. Cancer Res. 2019. PMID: 31662324 Free PMC article.
YAP1 Expression in SCLC Defines a Distinct Subtype With T-cell-Inflamed Phenotype.
Owonikoko TK, Dwivedi B, Chen Z, Zhang C, Barwick B, Ernani V, Zhang G, Gilbert-Ross M, Carlisle J, Khuri FR, Curran WJ, Ivanov AA, Fu H, Lonial S, Ramalingam SS, Sun SY, Waller EK, Sica GL. Owonikoko TK, et al. Among authors: sica gl. J Thorac Oncol. 2021 Mar;16(3):464-476. doi: 10.1016/j.jtho.2020.11.006. Epub 2020 Nov 25. J Thorac Oncol. 2021. PMID: 33248321 Free PMC article.
111 results