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Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation.
Sinner MF, Tucker NR, Lunetta KL, Ozaki K, Smith JG, Trompet S, Bis JC, Lin H, Chung MK, Nielsen JB, Lubitz SA, Krijthe BP, Magnani JW, Ye J, Gollob MH, Tsunoda T, Müller-Nurasyid M, Lichtner P, Peters A, Dolmatova E, Kubo M, Smith JD, Psaty BM, Smith NL, Jukema JW, Chasman DI, Albert CM, Ebana Y, Furukawa T, Macfarlane PW, Harris TB, Darbar D, Dörr M, Holst AG, Svendsen JH, Hofman A, Uitterlinden AG, Gudnason V, Isobe M, Malik R, Dichgans M, Rosand J, Van Wagoner DR; METASTROKE Consortium; AFGen Consortium; Benjamin EJ, Milan DJ, Melander O, Heckbert SR, Ford I, Liu Y, Barnard J, Olesen MS, Stricker BH, Tanaka T, Kääb S, Ellinor PT. Sinner MF, et al. Among authors: nielsen jb. Circulation. 2014 Oct 7;130(15):1225-35. doi: 10.1161/CIRCULATIONAHA.114.009892. Epub 2014 Aug 14. Circulation. 2014. PMID: 25124494 Free PMC article.
A novel nonsense variant in Nav1.5 cofactor MOG1 eliminates its sodium current increasing effect and may increase the risk of arrhythmias.
Olesen MS, Jensen NF, Holst AG, Nielsen JB, Tfelt-Hansen J, Jespersen T, Sajadieh A, Haunsø S, Lund JT, Calloe K, Schmitt N, Svendsen JH. Olesen MS, et al. Among authors: nielsen jb. Can J Cardiol. 2011 Jul-Aug;27(4):523.e17-23. doi: 10.1016/j.cjca.2011.01.003. Epub 2011 May 28. Can J Cardiol. 2011. PMID: 21621375 English, French.
High prevalence of long QT syndrome-associated SCN5A variants in patients with early-onset lone atrial fibrillation.
Olesen MS, Yuan L, Liang B, Holst AG, Nielsen N, Nielsen JB, Hedley PL, Christiansen M, Olesen SP, Haunsø S, Schmitt N, Jespersen T, Svendsen JH. Olesen MS, et al. Among authors: nielsen jb, nielsen n. Circ Cardiovasc Genet. 2012 Aug 1;5(4):450-9. doi: 10.1161/CIRCGENETICS.111.962597. Epub 2012 Jun 8. Circ Cardiovasc Genet. 2012. PMID: 22685113
793 results