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TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition.
Mandell MA, Jain A, Arko-Mensah J, Chauhan S, Kimura T, Dinkins C, Silvestri G, Münch J, Kirchhoff F, Simonsen A, Wei Y, Levine B, Johansen T, Deretic V. Mandell MA, et al. Among authors: silvestri g. Dev Cell. 2014 Aug 25;30(4):394-409. doi: 10.1016/j.devcel.2014.06.013. Epub 2014 Aug 7. Dev Cell. 2014. PMID: 25127057 Free PMC article.
Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1.
Schindler M, Münch J, Kutsch O, Li H, Santiago ML, Bibollet-Ruche F, Müller-Trutwin MC, Novembre FJ, Peeters M, Courgnaud V, Bailes E, Roques P, Sodora DL, Silvestri G, Sharp PM, Hahn BH, Kirchhoff F. Schindler M, et al. Among authors: silvestri g. Cell. 2006 Jun 16;125(6):1055-67. doi: 10.1016/j.cell.2006.04.033. Cell. 2006. PMID: 16777597 Free article.
Conservation of Nef function across highly diverse lineages of SIVsmm.
Schmökel J, Li H, Bailes E, Schindler M, Silvestri G, Hahn BH, Apetrei C, Kirchhoff F. Schmökel J, et al. Among authors: silvestri g. Retrovirology. 2009 Apr 9;6:36. doi: 10.1186/1742-4690-6-36. Retrovirology. 2009. PMID: 19358735 Free PMC article.
Low levels of SIV infection in sooty mangabey central memory CD⁴⁺ T cells are associated with limited CCR5 expression.
Paiardini M, Cervasi B, Reyes-Aviles E, Micci L, Ortiz AM, Chahroudi A, Vinton C, Gordon SN, Bosinger SE, Francella N, Hallberg PL, Cramer E, Schlub T, Chan ML, Riddick NE, Collman RG, Apetrei C, Pandrea I, Else J, Munch J, Kirchhoff F, Davenport MP, Brenchley JM, Silvestri G. Paiardini M, et al. Among authors: silvestri g. Nat Med. 2011 Jun 26;17(7):830-6. doi: 10.1038/nm.2395. Nat Med. 2011. PMID: 21706028 Free PMC article.
Link between primate lentiviral coreceptor usage and Nef function.
Schmökel J, Li H, Shabir A, Yu H, Geyer M, Silvestri G, Sodora DL, Hahn BH, Kirchhoff F. Schmökel J, et al. Among authors: silvestri g. Cell Rep. 2013 Nov 27;5(4):997-1009. doi: 10.1016/j.celrep.2013.10.028. Epub 2013 Nov 21. Cell Rep. 2013. PMID: 24268781 Free PMC article.
Lentiviral Nef proteins manipulate T cells in a subset-specific manner.
Yu H, Khalid M, Heigele A, Schmökel J, Usmani SM, van der Merwe J, Münch J, Silvestri G, Kirchhoff F. Yu H, et al. Among authors: silvestri g. J Virol. 2015 Feb;89(4):1986-2001. doi: 10.1128/JVI.03104-14. Epub 2014 Dec 10. J Virol. 2015. PMID: 25505066 Free PMC article.
Nef-Mediated CD3-TCR Downmodulation Dampens Acute Inflammation and Promotes SIV Immune Evasion.
Joas S, Sauermann U, Roshani B, Klippert A, Daskalaki M, Mätz-Rensing K, Stolte-Leeb N, Heigele A, Tharp GK, Gupta PM, Nelson S, Bosinger S, Parodi L, Giavedoni L, Silvestri G, Sauter D, Stahl-Hennig C, Kirchhoff F. Joas S, et al. Among authors: silvestri g. Cell Rep. 2020 Feb 18;30(7):2261-2274.e7. doi: 10.1016/j.celrep.2020.01.069. Cell Rep. 2020. PMID: 32075764 Free PMC article.
Limited HIV infection of central memory and stem cell memory CD4+ T cells is associated with lack of progression in viremic individuals.
Klatt NR, Bosinger SE, Peck M, Richert-Spuhler LE, Heigele A, Gile JP, Patel N, Taaffe J, Julg B, Camerini D, Torti C, Martin JN, Deeks SG, Sinclair E, Hecht FM, Lederman MM, Paiardini M, Kirchhoff F, Brenchley JM, Hunt PW, Silvestri G. Klatt NR, et al. Among authors: silvestri g. PLoS Pathog. 2014 Aug 28;10(8):e1004345. doi: 10.1371/journal.ppat.1004345. eCollection 2014 Aug. PLoS Pathog. 2014. PMID: 25167059 Free PMC article.
1,047 results