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Atheroprotective immunization with malondialdehyde-modified LDL is hapten specific and dependent on advanced MDA adducts: implications for development of an atheroprotective vaccine.
Gonen A, Hansen LF, Turner WW, Montano EN, Que X, Rafia A, Chou MY, Wiesner P, Tsiantoulas D, Corr M, VanNieuwenhze MS, Tsimikas S, Binder CJ, Witztum JL, Hartvigsen K. Gonen A, et al. Among authors: wiesner p. J Lipid Res. 2014 Oct;55(10):2137-55. doi: 10.1194/jlr.M053256. Epub 2014 Aug 20. J Lipid Res. 2014. PMID: 25143462 Free PMC article.
Oxidation-specific epitopes are danger-associated molecular patterns recognized by pattern recognition receptors of innate immunity.
Miller YI, Choi SH, Wiesner P, Fang L, Harkewicz R, Hartvigsen K, Boullier A, Gonen A, Diehl CJ, Que X, Montano E, Shaw PX, Tsimikas S, Binder CJ, Witztum JL. Miller YI, et al. Among authors: wiesner p. Circ Res. 2011 Jan 21;108(2):235-48. doi: 10.1161/CIRCRESAHA.110.223875. Circ Res. 2011. PMID: 21252151 Free PMC article. Review.
MCP-1 binds to oxidized LDL and is carried by lipoprotein(a) in human plasma.
Wiesner P, Tafelmeier M, Chittka D, Choi SH, Zhang L, Byun YS, Almazan F, Yang X, Iqbal N, Chowdhury P, Maisel A, Witztum JL, Handel TM, Tsimikas S, Miller YI. Wiesner P, et al. J Lipid Res. 2013 Jul;54(7):1877-83. doi: 10.1194/jlr.M036343. Epub 2013 May 10. J Lipid Res. 2013. PMID: 23667177 Free PMC article.
Low doses of lipopolysaccharide and minimally oxidized low-density lipoprotein cooperatively activate macrophages via nuclear factor kappa B and activator protein-1: possible mechanism for acceleration of atherosclerosis by subclinical endotoxemia.
Wiesner P, Choi SH, Almazan F, Benner C, Huang W, Diehl CJ, Gonen A, Butler S, Witztum JL, Glass CK, Miller YI. Wiesner P, et al. Circ Res. 2010 Jul 9;107(1):56-65. doi: 10.1161/CIRCRESAHA.110.218420. Epub 2010 May 20. Circ Res. 2010. PMID: 20489162 Free PMC article.
Oxidized cholesteryl esters and phospholipids in zebrafish larvae fed a high cholesterol diet: macrophage binding and activation.
Fang L, Harkewicz R, Hartvigsen K, Wiesner P, Choi SH, Almazan F, Pattison J, Deer E, Sayaphupha T, Dennis EA, Witztum JL, Tsimikas S, Miller YI. Fang L, et al. Among authors: wiesner p. J Biol Chem. 2010 Oct 15;285(42):32343-51. doi: 10.1074/jbc.M110.137257. Epub 2010 Aug 14. J Biol Chem. 2010. PMID: 20710028 Free PMC article.
In vivo detection of oxidation-specific epitopes in atherosclerotic lesions using biocompatible manganese molecular magnetic imaging probes.
Briley-Saebo KC, Nguyen TH, Saeboe AM, Cho YS, Ryu SK, Volkova ER, Dickson S, Leibundgut G, Wiesner P, Green S, Casanada F, Miller YI, Shaw W, Witztum JL, Fayad ZA, Tsimikas S. Briley-Saebo KC, et al. Among authors: wiesner p. J Am Coll Cardiol. 2012 Feb 7;59(6):616-26. doi: 10.1016/j.jacc.2011.10.881. J Am Coll Cardiol. 2012. PMID: 22300697 Free PMC article.
Control of angiogenesis by AIBP-mediated cholesterol efflux.
Fang L, Choi SH, Baek JS, Liu C, Almazan F, Ulrich F, Wiesner P, Taleb A, Deer E, Pattison J, Torres-Vázquez J, Li AC, Miller YI. Fang L, et al. Among authors: wiesner p. Nature. 2013 Jun 6;498(7452):118-22. doi: 10.1038/nature12166. Epub 2013 May 29. Nature. 2013. PMID: 23719382 Free PMC article.
96 results