Fronczek FR - Search Results

1

Orally bioavailable 6-chloro-7-methoxy-4(1H)-quinolones efficacious against multiple stages of Plasmodium.

Cross RM, Flanigan DL, Monastyrskyi A, LaCrue AN, Sáenz FE, Maignan JR, Mutka TS, White KL, Shackleford DM, Bathurst I, Fronczek FR, Wojtas L, Guida WC, Charman SA, Burrows JN, Kyle DE, Manetsch R. Cross RM, et al. Among authors: fronczek fr. J Med Chem. 2014 Nov 13;57(21):8860-79. doi: 10.1021/jm500942v. Epub 2014 Oct 22. J Med Chem. 2014. PMID: 25148516 Free PMC article.

2

Facile iterative synthesis of 2,5-terpyrimidinylenes as nonpeptidic alpha-helical mimics.

Anderson L, Zhou M, Sharma V, McLaughlin JM, Santiago DN, Fronczek FR, Guida WC, McLaughlin ML. Anderson L, et al. Among authors: fronczek fr. J Org Chem. 2010 Jun 18;75(12):4288-91. doi: 10.1021/jo100272d. J Org Chem. 2010. PMID: 20469918 Free PMC article.

3

Fluorescent properties and resonance energy transfer of 3,4-bis(2,4-difluorophenyl)-maleimide.

Nacheva KP, Maza WA, Myers DZ, Fronczek FR, Larsen RW, Manetsch R. Nacheva KP, et al. Among authors: fronczek fr. Org Biomol Chem. 2012 Oct 14;10(38):7840-6. doi: 10.1039/c2ob25981h. Org Biomol Chem. 2012. PMID: 22930038

4

Discovery and structure-activity relationship of novel 2,3-dihydrobenzofuran-7-carboxamide and 2,3-dihydrobenzofuran-3(2H)-one-7-carboxamide derivatives as poly(ADP-ribose)polymerase-1 inhibitors.

Patel MR, Bhatt A, Steffen JD, Chergui A, Murai J, Pommier Y, Pascal JM, Trombetta LD, Fronczek FR, Talele TT. Patel MR, et al. Among authors: fronczek fr. J Med Chem. 2014 Jul 10;57(13):5579-601. doi: 10.1021/jm5002502. Epub 2014 Jun 25. J Med Chem. 2014. PMID: 24922587 Free PMC article.

5

Synthesis and in vitro evaluation of BBB permeability, tumor cell uptake, and cytotoxicity of a series of carboranylporphyrin conjugates.

Bhupathiraju NV, Hu X, Zhou Z, Fronczek FR, Couraud PO, Romero IA, Weksler B, Vicente MG. Bhupathiraju NV, et al. Among authors: fronczek fr. J Med Chem. 2014 Aug 14;57(15):6718-28. doi: 10.1021/jm500786c. Epub 2014 Jul 31. J Med Chem. 2014. PMID: 25029034 Free PMC article.

6

Synthesis and in Vitro Studies of a Series of Carborane-Containing Boron Dipyrromethenes (BODIPYs).

Xuan S, Zhao N, Zhou Z, Fronczek FR, Vicente MG. Xuan S, et al. Among authors: fronczek fr. J Med Chem. 2016 Mar 10;59(5):2109-17. doi: 10.1021/acs.jmedchem.5b01783. Epub 2016 Feb 17. J Med Chem. 2016. PMID: 26849474 Free PMC article.

7

Development and Characterization of Novel and Selective Inhibitors of Cytochrome P450 CYP26A1, the Human Liver Retinoic Acid Hydroxylase.

Diaz P, Huang W, Keyari CM, Buttrick B, Price L, Guilloteau N, Tripathy S, Sperandio VG, Fronczek FR, Astruc-Diaz F, Isoherranen N. Diaz P, et al. Among authors: fronczek fr. J Med Chem. 2016 Mar 24;59(6):2579-95. doi: 10.1021/acs.jmedchem.5b01780. Epub 2016 Mar 15. J Med Chem. 2016. PMID: 26918322 Free PMC article.

8

Aryl morpholino triazenes inhibit cytochrome P450 1A1 and 1B1.

Lee D, Perez P, Jackson W, Chin T, Galbreath M, Fronczek FR, Isovitsch R, Iimoto DS. Lee D, et al. Among authors: fronczek fr. Bioorg Med Chem Lett. 2016 Jul 15;26(14):3243-3247. doi: 10.1016/j.bmcl.2016.05.064. Epub 2016 May 24. Bioorg Med Chem Lett. 2016. PMID: 27265259

9

Synthesis and cellular studies of nonaggregated water-soluble phthalocyanines.

Liu W, Jensen TJ, Fronczek FR, Hammer RP, Smith KM, Vicente MG. Liu W, et al. Among authors: fronczek fr. J Med Chem. 2005 Feb 24;48(4):1033-41. doi: 10.1021/jm049375b. J Med Chem. 2005. PMID: 15715471

10

Syntheses and properties of a series of cationic water-soluble phthalocyanines.

Li H, Jensen TJ, Fronczek FR, Vicente MG. Li H, et al. Among authors: fronczek fr. J Med Chem. 2008 Feb 14;51(3):502-11. doi: 10.1021/jm070781f. Epub 2008 Jan 12. J Med Chem. 2008. PMID: 18189349

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