Sinclair J - Search Results

1

Systematic evaluation of quantotypic peptides for targeted analysis of the human kinome.

Worboys JD, Sinclair J, Yuan Y, Jørgensen C. Worboys JD, et al. Among authors: sinclair j. Nat Methods. 2014 Oct;11(10):1041-4. doi: 10.1038/nmeth.3072. Epub 2014 Aug 24. Nat Methods. 2014. PMID: 25152083 Free PMC article.

2

Reproducible automated phosphopeptide enrichment using magnetic TiO2 and Ti-IMAC.

Tape CJ, Worboys JD, Sinclair J, Gourlay R, Vogt J, McMahon KM, Trost M, Lauffenburger DA, Lamont DJ, Jørgensen C. Tape CJ, et al. Among authors: sinclair j. Anal Chem. 2014 Oct 21;86(20):10296-302. doi: 10.1021/ac5025842. Epub 2014 Oct 2. Anal Chem. 2014. PMID: 25233145 Free PMC article.

3

Phosphoproteomic analysis of interacting tumor and endothelial cells identifies regulatory mechanisms of transendothelial migration.

Locard-Paulet M, Lim L, Veluscek G, McMahon K, Sinclair J, van Weverwijk A, Worboys JD, Yuan Y, Isacke CM, Jørgensen C. Locard-Paulet M, et al. Among authors: sinclair j. Sci Signal. 2016 Feb 9;9(414):ra15. doi: 10.1126/scisignal.aac5820. Sci Signal. 2016. PMID: 26861043 Free PMC article.

4

Identification of hypoxia-regulated proteins using MALDI-mass spectrometry imaging combined with quantitative proteomics.

Djidja MC, Chang J, Hadjiprocopis A, Schmich F, Sinclair J, Mršnik M, Schoof EM, Barker HE, Linding R, Jørgensen C, Erler JT. Djidja MC, et al. Among authors: sinclair j. J Proteome Res. 2014 May 2;13(5):2297-313. doi: 10.1021/pr401056c. Epub 2014 Apr 24. J Proteome Res. 2014. PMID: 24702160

5

PKA-regulated VASP phosphorylation promotes extrusion of transformed cells from the epithelium.

Anton KA, Sinclair J, Ohoka A, Kajita M, Ishikawa S, Benz PM, Renne T, Balda M, Jorgensen C, Matter K, Fujita Y. Anton KA, et al. Among authors: sinclair j. J Cell Sci. 2014 Aug 15;127(Pt 16):3425-33. doi: 10.1242/jcs.149674. Epub 2014 Jun 24. J Cell Sci. 2014. PMID: 24963131 Free PMC article.

6

Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.

So J, Pasculescu A, Dai AY, Williton K, James A, Nguyen V, Creixell P, Schoof EM, Sinclair J, Barrios-Rodiles M, Gu J, Krizus A, Williams R, Olhovsky M, Dennis JW, Wrana JL, Linding R, Jorgensen C, Pawson T, Colwill K. So J, et al. Among authors: sinclair j. Sci Signal. 2015 Apr 7;8(371):rs3. doi: 10.1126/scisignal.2005700. Sci Signal. 2015. PMID: 25852190

7

Inhibiting EGF receptor or SRC family kinase signaling overcomes BRAF inhibitor resistance in melanoma.

Girotti MR, Pedersen M, Sanchez-Laorden B, Viros A, Turajlic S, Niculescu-Duvaz D, Zambon A, Sinclair J, Hayes A, Gore M, Lorigan P, Springer C, Larkin J, Jorgensen C, Marais R. Girotti MR, et al. Among authors: sinclair j. Cancer Discov. 2013 Feb;3(2):158-67. doi: 10.1158/2159-8290.CD-12-0386. Epub 2012 Dec 14. Cancer Discov. 2013. PMID: 23242808 Free PMC article.

8

Proteomic profiling of ovarian cancer models using TMT-LC-MS/MS.

Sinclair J, Timms JF. Sinclair J, et al. Methods Mol Biol. 2013;1049:271-84. doi: 10.1007/978-1-62703-547-7_20. Methods Mol Biol. 2013. PMID: 23913223

9

A targeted glycoproteomic approach identifies cadherin-5 as a novel biomarker of metastatic breast cancer.

Fry SA, Sinclair J, Timms JF, Leathem AJ, Dwek MV. Fry SA, et al. Among authors: sinclair j. Cancer Lett. 2013 Jan 28;328(2):335-44. doi: 10.1016/j.canlet.2012.10.011. Epub 2012 Oct 16. Cancer Lett. 2013. PMID: 23079531

10

Quantitative profiling of serum samples using TMT protein labelling, fractionation and LC-MS/MS.

Sinclair J, Timms JF. Sinclair J, et al. Methods. 2011 Aug;54(4):361-9. doi: 10.1016/j.ymeth.2011.03.004. Epub 2011 Mar 21. Methods. 2011. PMID: 21397697

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