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IL-17/Th17 pathway is activated in acne lesions.
Kelhälä HL, Palatsi R, Fyhrquist N, Lehtimäki S, Väyrynen JP, Kallioinen M, Kubin ME, Greco D, Tasanen K, Alenius H, Bertino B, Carlavan I, Mehul B, Déret S, Reiniche P, Martel P, Marty C, Blume-Peytavi U, Voegel JJ, Lauerma A. Kelhälä HL, et al. Among authors: lehtimaki s. PLoS One. 2014 Aug 25;9(8):e105238. doi: 10.1371/journal.pone.0105238. eCollection 2014. PLoS One. 2014. PMID: 25153527 Free PMC article.
Isotretinoin treatment reduces acne lesions but not directly lesional acne inflammation.
Kelhälä HL, Fyhrquist N, Palatsi R, Lehtimäki S, Väyrynen JP, Kubin ME, Kallioinen M, Alenius H, Tasanen K, Lauerma A. Kelhälä HL, et al. Among authors: lehtimaki s. Exp Dermatol. 2016 Jun;25(6):477-8. doi: 10.1111/exd.12971. Epub 2016 Mar 2. Exp Dermatol. 2016. PMID: 26845242 Clinical Trial. No abstract available.
Foxp3+ cells control Th2 responses in a murine model of atopic dermatitis.
Fyhrquist N, Lehtimäki S, Lahl K, Savinko T, Lappeteläinen AM, Sparwasser T, Wolff H, Lauerma A, Alenius H. Fyhrquist N, et al. Among authors: lehtimaki s. J Invest Dermatol. 2012 Jun;132(6):1672-80. doi: 10.1038/jid.2012.40. Epub 2012 Mar 8. J Invest Dermatol. 2012. PMID: 22402436 Free article.
Topical superantigen exposure induces epidermal accumulation of CD8+ T cells, a mixed Th1/Th2-type dermatitis and vigorous production of IgE antibodies in the murine model of atopic dermatitis.
Savinko T, Lauerma A, Lehtimäki S, Gombert M, Majuri ML, Fyhrquist-Vanni N, Dieu-Nosjean MC, Kemeny L, Wolff H, Homey B, Alenius H. Savinko T, et al. Among authors: lehtimaki s. J Immunol. 2005 Dec 15;175(12):8320-6. doi: 10.4049/jimmunol.175.12.8320. J Immunol. 2005. PMID: 16339573
45 results