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IL-17/Th17 pathway is activated in acne lesions.
Kelhälä HL, Palatsi R, Fyhrquist N, Lehtimäki S, Väyrynen JP, Kallioinen M, Kubin ME, Greco D, Tasanen K, Alenius H, Bertino B, Carlavan I, Mehul B, Déret S, Reiniche P, Martel P, Marty C, Blume-Peytavi U, Voegel JJ, Lauerma A. Kelhälä HL, et al. Among authors: vayrynen jp. PLoS One. 2014 Aug 25;9(8):e105238. doi: 10.1371/journal.pone.0105238. eCollection 2014. PLoS One. 2014. PMID: 25153527 Free PMC article.
Bayesian risk prediction model for colorectal cancer mortality through integration of clinicopathologic and genomic data.
Zhao M, Lau MC, Haruki K, Väyrynen JP, Gurjao C, Väyrynen SA, Dias Costa A, Borowsky J, Fujiyoshi K, Arima K, Hamada T, Lennerz JK, Fuchs CS, Nishihara R, Chan AT, Ng K, Zhang X, Meyerhardt JA, Song M, Wang M, Giannakis M, Nowak JA, Yu KH, Ugai T, Ogino S. Zhao M, et al. Among authors: vayrynen jp. NPJ Precis Oncol. 2023 Jun 10;7(1):57. doi: 10.1038/s41698-023-00406-8. NPJ Precis Oncol. 2023. PMID: 37301916 Free PMC article.
Association of Machine Learning-Based Assessment of Tumor-Infiltrating Lymphocytes on Standard Histologic Images With Outcomes of Immunotherapy in Patients With NSCLC.
Rakaee M, Adib E, Ricciuti B, Sholl LM, Shi W, Alessi JV, Cortellini A, Fulgenzi CAM, Viola P, Pinato DJ, Hashemi S, Bahce I, Houda I, Ulas EB, Radonic T, Väyrynen JP, Richardsen E, Jamaly S, Andersen S, Donnem T, Awad MM, Kwiatkowski DJ. Rakaee M, et al. Among authors: vayrynen jp. JAMA Oncol. 2023 Jan 1;9(1):51-60. doi: 10.1001/jamaoncol.2022.4933. JAMA Oncol. 2023. PMID: 36394839 Free PMC article.
Spatially resolved multimarker evaluation of CD274 (PD-L1)/PDCD1 (PD-1) immune checkpoint expression and macrophage polarisation in colorectal cancer.
Elomaa H, Ahtiainen M, Väyrynen SA, Ogino S, Nowak JA, Lau MC, Helminen O, Wirta EV, Seppälä TT, Böhm J, Mecklin JP, Kuopio T, Väyrynen JP. Elomaa H, et al. Among authors: vayrynen jp, vayrynen sa. Br J Cancer. 2023 Jun;128(11):2104-2115. doi: 10.1038/s41416-023-02238-6. Epub 2023 Mar 31. Br J Cancer. 2023. PMID: 37002343 Free PMC article.
The prognostic role of tumor budding and tumor-stroma ratio in pulmonary metastasis of colorectal carcinoma.
Karjula T, Kemi N, Niskakangas A, Mustonen O, Puro I, Pohjanen VM, Kuopio T, Elomaa H, Ahtiainen M, Mecklin JP, Seppälä TT, Wirta EV, Sihvo E, Väyrynen JP, Yannopoulos F, Helminen O. Karjula T, et al. Among authors: vayrynen jp. Eur J Surg Oncol. 2023 Jul;49(7):1298-1306. doi: 10.1016/j.ejso.2023.02.009. Epub 2023 Feb 21. Eur J Surg Oncol. 2023. PMID: 36841693 Free article.
Histopathology images predict multi-omics aberrations and prognoses in colorectal cancer patients.
Tsai PC, Lee TH, Kuo KC, Su FY, Lee TM, Marostica E, Ugai T, Zhao M, Lau MC, Väyrynen JP, Giannakis M, Takashima Y, Kahaki SM, Wu K, Song M, Meyerhardt JA, Chan AT, Chiang JH, Nowak J, Ogino S, Yu KH. Tsai PC, et al. Among authors: vayrynen jp. Nat Commun. 2023 Apr 13;14(1):2102. doi: 10.1038/s41467-023-37179-4. Nat Commun. 2023. PMID: 37055393 Free PMC article.
A pan-cancer analysis shows immunoevasive characteristics in NRF2 hyperactive squamous malignancies.
Härkönen J, Pölönen P, Deen AJ, Selvarajan I, Teppo HR, Dimova EY, Kietzmann T, Ahtiainen M, Väyrynen JP, Väyrynen SA, Elomaa H, Tynkkynen N, Eklund T, Kuopio T, Talvitie EM, Taimen P, Kallajoki M, Kaikkonen MU, Heinäniemi M, Levonen AL. Härkönen J, et al. Among authors: vayrynen jp, vayrynen sa. Redox Biol. 2023 May;61:102644. doi: 10.1016/j.redox.2023.102644. Epub 2023 Feb 27. Redox Biol. 2023. PMID: 36867945 Free PMC article.
Tertiary lymphoid structures in pulmonary metastases of microsatellite stable colorectal cancer.
Karjula T, Niskakangas A, Mustonen O, Puro I, Elomaa H, Ahtiainen M, Kuopio T, Mecklin JP, Seppälä TT, Wirta EV, Sihvo E, Yannopoulos F, Helminen O, Väyrynen JP. Karjula T, et al. Among authors: vayrynen jp. Virchows Arch. 2023 Jul;483(1):21-32. doi: 10.1007/s00428-023-03577-8. Epub 2023 Jun 20. Virchows Arch. 2023. PMID: 37337034 Free PMC article.
Inverse relationship between Fusobacterium nucleatum amount and tumor CD274 (PD-L1) expression in colorectal carcinoma.
Ugai T, Shimizu T, Kawamura H, Ugai S, Takashima Y, Usui G, Väyrynen JP, Okadome K, Haruki K, Akimoto N, Masugi Y, da Silva A, Mima K, Zhang X, Chan AT, Wang M, Garrett WS, Freeman GJ, Meyerhardt JA, Nowak JA, Song M, Giannakis M, Ogino S. Ugai T, et al. Among authors: vayrynen jp. Clin Transl Immunology. 2023 Aug 2;12(8):e1453. doi: 10.1002/cti2.1453. eCollection 2023. Clin Transl Immunology. 2023. PMID: 37538192 Free PMC article.
Spatially Resolved Single-Cell Assessment of Pancreatic Cancer Expression Subtypes Reveals Co-expressor Phenotypes and Extensive Intratumoral Heterogeneity.
Williams HL, Dias Costa A, Zhang J, Raghavan S, Winter PS, Kapner KS, Ginebaugh SP, Väyrynen SA, Väyrynen JP, Yuan C, Navia AW, Wang J, Yang A, Bosse TL, Kalekar RL, Lowder KE, Lau MC, Elganainy D, Morales-Oyarvide V, Rubinson DA, Singh H, Perez K, Cleary JM, Clancy TE, Wang J, Mancias JD, Brais LK, Hill ER, Kozak MM, Linehan DC, Dunne RF, Chang DT, Koong AC, Hezel AF, Hahn WC, Shalek AK, Aguirre AJ, Nowak JA, Wolpin BM. Williams HL, et al. Among authors: vayrynen jp, vayrynen sa. Cancer Res. 2023 Feb 3;83(3):441-455. doi: 10.1158/0008-5472.CAN-22-3050. Cancer Res. 2023. PMID: 36459568 Free PMC article.
94 results