Keefer LK - Search Results

1

Analysis of the HNO and NO donating properties of alicyclic amine diazeniumdiolates.

Bharadwaj G, Benini PG, Basudhar D, Ramos-Colon CN, Johnson GM, Larriva MM, Keefer LK, Andrei D, Miranda KM. Bharadwaj G, et al. Among authors: keefer lk. Nitric Oxide. 2014 Nov 15;42:70-8. doi: 10.1016/j.niox.2014.08.013. Epub 2014 Sep 2. Nitric Oxide. 2014. PMID: 25192820 Free PMC article.

2

Comparison of the NO and HNO donating properties of diazeniumdiolates: primary amine adducts release HNO in Vivo.

Miranda KM, Katori T, Torres de Holding CL, Thomas L, Ridnour LA, McLendon WJ, Cologna SM, Dutton AS, Champion HC, Mancardi D, Tocchetti CG, Saavedra JE, Keefer LK, Houk KN, Fukuto JM, Kass DA, Paolocci N, Wink DA. Miranda KM, et al. Among authors: keefer lk. J Med Chem. 2005 Dec 29;48(26):8220-8. doi: 10.1021/jm050151i. J Med Chem. 2005. PMID: 16366603

3

Dual mechanisms of HNO generation by a nitroxyl prodrug of the diazeniumdiolate (NONOate) class.

Andrei D, Salmon DJ, Donzelli S, Wahab A, Klose JR, Citro ML, Saavedra JE, Wink DA, Miranda KM, Keefer LK. Andrei D, et al. Among authors: keefer lk. J Am Chem Soc. 2010 Nov 24;132(46):16526-32. doi: 10.1021/ja106552p. Epub 2010 Oct 29. J Am Chem Soc. 2010. PMID: 21033665 Free PMC article.

4

HNO and NO release from a primary amine-based diazeniumdiolate as a function of pH.

Salmon DJ, Torres de Holding CL, Thomas L, Peterson KV, Goodman GP, Saavedra JE, Srinivasan A, Davies KM, Keefer LK, Miranda KM. Salmon DJ, et al. Among authors: keefer lk. Inorg Chem. 2011 Apr 18;50(8):3262-70. doi: 10.1021/ic101736e. Epub 2011 Mar 15. Inorg Chem. 2011. PMID: 21405089 Free PMC article.

5

Aryl bis(diazeniumdiolates): potent inducers of S-glutathionylation of cellular proteins and their in vitro antiproliferative activities.

Andrei D, Maciag AE, Chakrapani H, Citro ML, Keefer LK, Saavedra JE. Andrei D, et al. Among authors: keefer lk. J Med Chem. 2008 Dec 25;51(24):7944-52. doi: 10.1021/jm800831y. J Med Chem. 2008. PMID: 19053760 Free PMC article.

6

Enzymatic generation of the NO/HNO-releasing IPA/NO anion at controlled rates in physiological media using β-galactosidase.

Holland RJ, Paulisch R, Cao Z, Keefer LK, Saavedra JE, Donzelli S. Holland RJ, et al. Among authors: keefer lk. Nitric Oxide. 2013 Nov 30;35:131-6. doi: 10.1016/j.niox.2013.10.003. Epub 2013 Oct 11. Nitric Oxide. 2013. PMID: 24126017 Free PMC article.

7

Chemistry of the diazeniumdiolates. I. Structural and spectral characteristics of the [N(O)NO]- functional group.

Keefer LK, Flippen-Anderson JL, George C, Shanklin AP, Dunams TM, Christodoulou D, Saavedra JE, Sagan ES, Bohle DS. Keefer LK, et al. Nitric Oxide. 2001 Aug;5(4):377-94. doi: 10.1006/niox.2001.0359. Nitric Oxide. 2001. PMID: 11485376

8

Mechanistic insight into exclusive nitric oxide recovery from a carbon-bound diazeniumdiolate.

Arnold EV, Citro ML, Saavedra EA, Davies KM, Keefer LK, Hrabie JA. Arnold EV, et al. Among authors: keefer lk. Nitric Oxide. 2002 Sep;7(2):103-8. doi: 10.1016/s1089-8603(02)00101-5. Nitric Oxide. 2002. PMID: 12223179

9

Decoding nitric oxide release rates of amine-based diazeniumdiolates.

Wang YN, Collins J, Holland RJ, Keefer LK, Ivanic J. Wang YN, et al. Among authors: keefer lk. J Phys Chem A. 2013 Aug 1;117(30):6671-7. doi: 10.1021/jp404589p. Epub 2013 Jul 23. J Phys Chem A. 2013. PMID: 23834533 Free PMC article.

10

Nitric oxide (NO)- and nitroxyl (HNO)-generating diazeniumdiolates (NONOates): emerging commercial opportunities.

Keefer LK. Keefer LK. Curr Top Med Chem. 2005;5(7):625-36. doi: 10.2174/1568026054679380. Curr Top Med Chem. 2005. PMID: 16101424 Review.

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