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Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism.
Fadista J, Vikman P, Laakso EO, Mollet IG, Esguerra JL, Taneera J, Storm P, Osmark P, Ladenvall C, Prasad RB, Hansson KB, Finotello F, Uvebrant K, Ofori JK, Di Camillo B, Krus U, Cilio CM, Hansson O, Eliasson L, Rosengren AH, Renström E, Wollheim CB, Groop L. Fadista J, et al. Among authors: rosengren ah. Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):13924-9. doi: 10.1073/pnas.1402665111. Epub 2014 Sep 8. Proc Natl Acad Sci U S A. 2014. PMID: 25201977 Free PMC article.
Why treatment fails in type 2 diabetes.
Rosengren A, Jing X, Eliasson L, Renström E. Rosengren A, et al. PLoS Med. 2008 Oct 28;5(10):e215. doi: 10.1371/journal.pmed.0050215. PLoS Med. 2008. PMID: 18959474 Free PMC article.
Overexpression of alpha2A-adrenergic receptors contributes to type 2 diabetes.
Rosengren AH, Jokubka R, Tojjar D, Granhall C, Hansson O, Li DQ, Nagaraj V, Reinbothe TM, Tuncel J, Eliasson L, Groop L, Rorsman P, Salehi A, Lyssenko V, Luthman H, Renström E. Rosengren AH, et al. Science. 2010 Jan 8;327(5962):217-20. doi: 10.1126/science.1176827. Epub 2009 Nov 19. Science. 2010. PMID: 19965390
GLP-1 inhibits and adrenaline stimulates glucagon release by differential modulation of N- and L-type Ca2+ channel-dependent exocytosis.
De Marinis YZ, Salehi A, Ward CE, Zhang Q, Abdulkader F, Bengtsson M, Braha O, Braun M, Ramracheya R, Amisten S, Habib AM, Moritoh Y, Zhang E, Reimann F, Rosengren A, Shibasaki T, Gribble F, Renström E, Seino S, Eliasson L, Rorsman P. De Marinis YZ, et al. Cell Metab. 2010 Jun 9;11(6):543-553. doi: 10.1016/j.cmet.2010.04.007. Cell Metab. 2010. PMID: 20519125 Free PMC article.
44 results