Mieczkowski PA - Search Results

1

Heterogeneous polymerase fidelity and mismatch repair bias genome variation and composition.

Lujan SA, Clausen AR, Clark AB, MacAlpine HK, MacAlpine DM, Malc EP, Mieczkowski PA, Burkholder AB, Fargo DC, Gordenin DA, Kunkel TA. Lujan SA, et al. Among authors: mieczkowski pa. Genome Res. 2014 Nov;24(11):1751-64. doi: 10.1101/gr.178335.114. Epub 2014 Sep 12. Genome Res. 2014. PMID: 25217194 Free PMC article.

2

Double-strand breaks associated with repetitive DNA can reshape the genome.

Argueso JL, Westmoreland J, Mieczkowski PA, Gawel M, Petes TD, Resnick MA. Argueso JL, et al. Among authors: mieczkowski pa. Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11845-50. doi: 10.1073/pnas.0804529105. Epub 2008 Aug 13. Proc Natl Acad Sci U S A. 2008. PMID: 18701715 Free PMC article.

3

Genome structure of a Saccharomyces cerevisiae strain widely used in bioethanol production.

Argueso JL, Carazzolle MF, Mieczkowski PA, Duarte FM, Netto OV, Missawa SK, Galzerani F, Costa GG, Vidal RO, Noronha MF, Dominska M, Andrietta MG, Andrietta SR, Cunha AF, Gomes LH, Tavares FC, Alcarde AR, Dietrich FS, McCusker JH, Petes TD, Pereira GA. Argueso JL, et al. Among authors: mieczkowski pa. Genome Res. 2009 Dec;19(12):2258-70. doi: 10.1101/gr.091777.109. Epub 2009 Oct 7. Genome Res. 2009. PMID: 19812109 Free PMC article.

4

Genome-wide model for the normal eukaryotic DNA replication fork.

Larrea AA, Lujan SA, Nick McElhinny SA, Mieczkowski PA, Resnick MA, Gordenin DA, Kunkel TA. Larrea AA, et al. Among authors: mieczkowski pa. Proc Natl Acad Sci U S A. 2010 Oct 12;107(41):17674-9. doi: 10.1073/pnas.1010178107. Epub 2010 Sep 27. Proc Natl Acad Sci U S A. 2010. PMID: 20876092 Free PMC article.

5

Damage-induced localized hypermutability.

Burch LH, Yang Y, Sterling JF, Roberts SA, Chao FG, Xu H, Zhang L, Walsh J, Resnick MA, Mieczkowski PA, Gordenin DA. Burch LH, et al. Among authors: mieczkowski pa. Cell Cycle. 2011 Apr 1;10(7):1073-85. doi: 10.4161/cc.10.7.15319. Epub 2011 Apr 1. Cell Cycle. 2011. PMID: 21406975 Free PMC article.

6

High-resolution genome-wide analysis of irradiated (UV and γ-rays) diploid yeast cells reveals a high frequency of genomic loss of heterozygosity (LOH) events.

St Charles J, Hazkani-Covo E, Yin Y, Andersen SL, Dietrich FS, Greenwell PW, Malc E, Mieczkowski P, Petes TD. St Charles J, et al. Genetics. 2012 Apr;190(4):1267-84. doi: 10.1534/genetics.111.137927. Epub 2012 Jan 20. Genetics. 2012. PMID: 22267500 Free PMC article.

7

Clustered mutations in yeast and in human cancers can arise from damaged long single-strand DNA regions.

Roberts SA, Sterling J, Thompson C, Harris S, Mav D, Shah R, Klimczak LJ, Kryukov GV, Malc E, Mieczkowski PA, Resnick MA, Gordenin DA. Roberts SA, et al. Among authors: mieczkowski pa. Mol Cell. 2012 May 25;46(4):424-35. doi: 10.1016/j.molcel.2012.03.030. Epub 2012 May 17. Mol Cell. 2012. PMID: 22607975 Free PMC article.

8

The generation of oxidative stress-induced rearrangements in Saccharomyces cerevisiae mtDNA is dependent on the Nuc1 (EndoG/ExoG) nuclease and is enhanced by inactivation of the MRX complex.

Dzierzbicki P, Kaniak-Golik A, Malc E, Mieczkowski P, Ciesla Z. Dzierzbicki P, et al. Mutat Res. 2012 Dec;740(1-2):21-33. doi: 10.1016/j.mrfmmm.2012.12.004. Epub 2012 Dec 28. Mutat Res. 2012. PMID: 23276591

9

Gene copy-number variation in haploid and diploid strains of the yeast Saccharomyces cerevisiae.

Zhang H, Zeidler AF, Song W, Puccia CM, Malc E, Greenwell PW, Mieczkowski PA, Petes TD, Argueso JL. Zhang H, et al. Among authors: mieczkowski pa. Genetics. 2013 Mar;193(3):785-801. doi: 10.1534/genetics.112.146522. Epub 2013 Jan 10. Genetics. 2013. PMID: 23307895 Free PMC article.

10

Variant calling in low-coverage whole genome sequencing of a Native American population sample.

Bizon C, Spiegel M, Chasse SA, Gizer IR, Li Y, Malc EP, Mieczkowski PA, Sailsbery JK, Wang X, Ehlers CL, Wilhelmsen KC. Bizon C, et al. Among authors: mieczkowski pa. BMC Genomics. 2014 Jan 30;15:85. doi: 10.1186/1471-2164-15-85. BMC Genomics. 2014. PMID: 24479562 Free PMC article.

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