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A high-resolution map of transcriptional repression.
Liang Z, Brown KE, Carroll T, Taylor B, Vidal IF, Hendrich B, Rueda D, Fisher AG, Merkenschlager M. Liang Z, et al. Elife. 2017 Mar 20;6:e22767. doi: 10.7554/eLife.22767. Elife. 2017. PMID: 28318487 Free PMC article.
Decoding non-random mutational signatures at Cas9 targeted sites.
Taheri-Ghahfarokhi A, Taylor BJM, Nitsch R, Lundin A, Cavallo AL, Madeyski-Bengtson K, Karlsson F, Clausen M, Hicks R, Mayr LM, Bohlooly-Y M, Maresca M. Taheri-Ghahfarokhi A, et al. Nucleic Acids Res. 2018 Sep 19;46(16):8417-8434. doi: 10.1093/nar/gky653. Nucleic Acids Res. 2018. PMID: 30032200 Free PMC article.
Universal toxin-based selection for precise genome engineering in human cells.
Li S, Akrap N, Cerboni S, Porritt MJ, Wimberger S, Lundin A, Möller C, Firth M, Gordon E, Lazovic B, Sieńska A, Pane LS, Coelho MA, Ciotta G, Pellegrini G, Sini M, Xu X, Mitra S, Bohlooly-Y M, Taylor BJM, Sienski G, Maresca M. Li S, et al. Nat Commun. 2021 Jan 21;12(1):497. doi: 10.1038/s41467-020-20810-z. Nat Commun. 2021. PMID: 33479216 Free PMC article.
DNA stretching induces Cas9 off-target activity.
Newton MD, Taylor BJ, Driessen RPC, Roos L, Cvetesic N, Allyjaun S, Lenhard B, Cuomo ME, Rueda DS. Newton MD, et al. Among authors: taylor bj. Nat Struct Mol Biol. 2019 Mar;26(3):185-192. doi: 10.1038/s41594-019-0188-z. Epub 2019 Feb 25. Nat Struct Mol Biol. 2019. PMID: 30804513 Free PMC article.
470 results