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Myb overexpression overrides androgen depletion-induced cell cycle arrest and apoptosis in prostate cancer cells, and confers aggressive malignant traits: potential role in castration resistance.
Srivastava SK, Bhardwaj A, Singh S, Arora S, McClellan S, Grizzle WE, Reed E, Singh AP. Srivastava SK, et al. Among authors: bhardwaj a. Carcinogenesis. 2012 Jun;33(6):1149-57. doi: 10.1093/carcin/bgs134. Epub 2012 Mar 19. Carcinogenesis. 2012. PMID: 22431717 Free PMC article.
CXCL12/CXCR4 protein signaling axis induces sonic hedgehog expression in pancreatic cancer cells via extracellular regulated kinase- and Akt kinase-mediated activation of nuclear factor κB: implications for bidirectional tumor-stromal interactions.
Singh AP, Arora S, Bhardwaj A, Srivastava SK, Kadakia MP, Wang B, Grizzle WE, Owen LB, Singh S. Singh AP, et al. Among authors: bhardwaj a. J Biol Chem. 2012 Nov 9;287(46):39115-24. doi: 10.1074/jbc.M112.409581. Epub 2012 Sep 20. J Biol Chem. 2012. PMID: 22995914 Free PMC article.
An undesired effect of chemotherapy: gemcitabine promotes pancreatic cancer cell invasiveness through reactive oxygen species-dependent, nuclear factor κB- and hypoxia-inducible factor 1α-mediated up-regulation of CXCR4.
Arora S, Bhardwaj A, Singh S, Srivastava SK, McClellan S, Nirodi CS, Piazza GA, Grizzle WE, Owen LB, Singh AP. Arora S, et al. Among authors: bhardwaj a. J Biol Chem. 2013 Jul 19;288(29):21197-21207. doi: 10.1074/jbc.M113.484576. Epub 2013 Jun 5. J Biol Chem. 2013. PMID: 23740244 Free PMC article.
Resistin and interleukin-6 exhibit racially-disparate expression in breast cancer patients, display molecular association and promote growth and aggressiveness of tumor cells through STAT3 activation.
Deshmukh SK, Srivastava SK, Bhardwaj A, Singh AP, Tyagi N, Marimuthu S, Dyess DL, Dal Zotto V, Carter JE, Singh S. Deshmukh SK, et al. Among authors: bhardwaj a. Oncotarget. 2015 May 10;6(13):11231-41. doi: 10.18632/oncotarget.3591. Oncotarget. 2015. PMID: 25868978 Free PMC article.
1,504 results