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Genetic variation in the FAS gene and associations with acute lung injury.
Glavan BJ, Holden TD, Goss CH, Black RA, Neff MJ, Nathens AB, Martin TR, Wurfel MM; ARDSnet Investigators. Glavan BJ, et al. Among authors: wurfel mm. Am J Respir Crit Care Med. 2011 Feb 1;183(3):356-63. doi: 10.1164/rccm.201003-0351OC. Epub 2010 Sep 2. Am J Respir Crit Care Med. 2011. PMID: 20813889 Free PMC article.
ANGPT2 genetic variant is associated with trauma-associated acute lung injury and altered plasma angiopoietin-2 isoform ratio.
Meyer NJ, Li M, Feng R, Bradfield J, Gallop R, Bellamy S, Fuchs BD, Lanken PN, Albelda SM, Rushefski M, Aplenc R, Abramova H, Atochina-Vasserman EN, Beers MF, Calfee CS, Cohen MJ, Pittet JF, Christiani DC, O'Keefe GE, Ware LB, May AK, Wurfel MM, Hakonarson H, Christie JD. Meyer NJ, et al. Among authors: wurfel mm. Am J Respir Crit Care Med. 2011 May 15;183(10):1344-53. doi: 10.1164/rccm.201005-0701OC. Epub 2011 Jan 21. Am J Respir Crit Care Med. 2011. PMID: 21257790 Free PMC article.
Genome wide association identifies PPFIA1 as a candidate gene for acute lung injury risk following major trauma.
Christie JD, Wurfel MM, Feng R, O'Keefe GE, Bradfield J, Ware LB, Christiani DC, Calfee CS, Cohen MJ, Matthay M, Meyer NJ, Kim C, Li M, Akey J, Barnes KC, Sevransky J, Lanken PN, May AK, Aplenc R, Maloney JP, Hakonarson H; Trauma ALI SNP Consortium (TASC) investigators. Christie JD, et al. Among authors: wurfel mm. PLoS One. 2012;7(1):e28268. doi: 10.1371/journal.pone.0028268. Epub 2012 Jan 25. PLoS One. 2012. PMID: 22295056 Free PMC article.
Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis.
Emond MJ, Louie T, Emerson J, Zhao W, Mathias RA, Knowles MR, Wright FA, Rieder MJ, Tabor HK, Nickerson DA, Barnes KC; National Heart, Lung, and Blood Institute (NHLBI) GO Exome Sequencing Project; Lung GO; Gibson RL, Bamshad MJ. Emond MJ, et al. Nat Genet. 2012 Jul 8;44(8):886-9. doi: 10.1038/ng.2344. Nat Genet. 2012. PMID: 22772370 Free PMC article.
Optimal unified approach for rare-variant association testing with application to small-sample case-control whole-exome sequencing studies.
Lee S, Emond MJ, Bamshad MJ, Barnes KC, Rieder MJ, Nickerson DA; NHLBI GO Exome Sequencing Project—ESP Lung Project Team; Christiani DC, Wurfel MM, Lin X. Lee S, et al. Among authors: wurfel mm. Am J Hum Genet. 2012 Aug 10;91(2):224-37. doi: 10.1016/j.ajhg.2012.06.007. Epub 2012 Aug 2. Am J Hum Genet. 2012. PMID: 22863193 Free PMC article.
Distinct and replicable genetic risk factors for acute respiratory distress syndrome of pulmonary or extrapulmonary origin.
Tejera P, Meyer NJ, Chen F, Feng R, Zhao Y, O'Mahony DS, Li L, Sheu CC, Zhai R, Wang Z, Su L, Bajwa E, Ahasic AM, Clardy PF, Gong MN, Frank AJ, Lanken PN, Thompson BT, Christie JD, Wurfel MM, O'Keefe GE, Christiani DC. Tejera P, et al. Among authors: wurfel mm. J Med Genet. 2012 Nov;49(11):671-80. doi: 10.1136/jmedgenet-2012-100972. Epub 2012 Oct 9. J Med Genet. 2012. PMID: 23048207 Free PMC article.
Exome sequencing and genome-wide linkage analysis in 17 families illustrate the complex contribution of TTN truncating variants to dilated cardiomyopathy.
Norton N, Li D, Rampersaud E, Morales A, Martin ER, Zuchner S, Guo S, Gonzalez M, Hedges DJ, Robertson PD, Krumm N, Nickerson DA, Hershberger RE; National Heart, Lung, and Blood Institute GO Exome Sequencing Project and the Exome Sequencing Project Family Studies Project Team. Norton N, et al. Circ Cardiovasc Genet. 2013 Apr;6(2):144-53. doi: 10.1161/CIRCGENETICS.111.000062. Epub 2013 Feb 15. Circ Cardiovasc Genet. 2013. PMID: 23418287 Free PMC article.
160 results