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Page 1
mTOR- and HIF-1α-mediated aerobic glycolysis as metabolic basis for trained immunity.
Cheng SC, Quintin J, Cramer RA, Shepardson KM, Saeed S, Kumar V, Giamarellos-Bourboulis EJ, Martens JH, Rao NA, Aghajanirefah A, Manjeri GR, Li Y, Ifrim DC, Arts RJ, van der Veer BM, Deen PM, Logie C, O'Neill LA, Willems P, van de Veerdonk FL, van der Meer JW, Ng A, Joosten LA, Wijmenga C, Stunnenberg HG, Xavier RJ, Netea MG. Cheng SC, et al. Among authors: ifrim dc. Science. 2014 Sep 26;345(6204):1250684. doi: 10.1126/science.1250684. Science. 2014. PMID: 25258083 Free PMC article.
Candida albicans infection affords protection against reinfection via functional reprogramming of monocytes.
Quintin J, Saeed S, Martens JHA, Giamarellos-Bourboulis EJ, Ifrim DC, Logie C, Jacobs L, Jansen T, Kullberg BJ, Wijmenga C, Joosten LAB, Xavier RJ, van der Meer JWM, Stunnenberg HG, Netea MG. Quintin J, et al. Among authors: ifrim dc. Cell Host Microbe. 2012 Aug 16;12(2):223-32. doi: 10.1016/j.chom.2012.06.006. Cell Host Microbe. 2012. PMID: 22901542 Free PMC article.
Bacille Calmette-Guerin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes.
Kleinnijenhuis J, Quintin J, Preijers F, Joosten LA, Ifrim DC, Saeed S, Jacobs C, van Loenhout J, de Jong D, Stunnenberg HG, Xavier RJ, van der Meer JW, van Crevel R, Netea MG. Kleinnijenhuis J, et al. Among authors: ifrim dc. Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17537-42. doi: 10.1073/pnas.1202870109. Epub 2012 Sep 17. Proc Natl Acad Sci U S A. 2012. PMID: 22988082 Free PMC article.
Role of Dectin-2 for host defense against systemic infection with Candida glabrata.
Ifrim DC, Bain JM, Reid DM, Oosting M, Verschueren I, Gow NA, van Krieken JH, Brown GD, Kullberg BJ, Joosten LA, van der Meer JW, Koentgen F, Erwig LP, Quintin J, Netea MG. Ifrim DC, et al. Infect Immun. 2014 Mar;82(3):1064-73. doi: 10.1128/IAI.01189-13. Epub 2013 Dec 16. Infect Immun. 2014. PMID: 24343653 Free PMC article.
Antifungal innate immunity: recognition and inflammatory networks.
Becker KL, Ifrim DC, Quintin J, Netea MG, van de Veerdonk FL. Becker KL, et al. Among authors: ifrim dc. Semin Immunopathol. 2015 Mar;37(2):107-16. doi: 10.1007/s00281-014-0467-z. Epub 2014 Dec 20. Semin Immunopathol. 2015. PMID: 25527294 Review.
The Role of Dectin-2 for Host Defense Against Disseminated Candidiasis.
Ifrim DC, Quintin J, Courjol F, Verschueren I, van Krieken JH, Koentgen F, Fradin C, Gow NA, Joosten LA, van der Meer JW, van de Veerdonk F, Netea MG. Ifrim DC, et al. J Interferon Cytokine Res. 2016 Apr;36(4):267-76. doi: 10.1089/jir.2015.0040. Epub 2016 Jan 27. J Interferon Cytokine Res. 2016. PMID: 27046240 Free PMC article.
Fungal Chitin Induces Trained Immunity in Human Monocytes during Cross-talk of the Host with Saccharomyces cerevisiae.
Rizzetto L, Ifrim DC, Moretti S, Tocci N, Cheng SC, Quintin J, Renga G, Oikonomou V, De Filippo C, Weil T, Blok BA, Lenucci MS, Santos MA, Romani L, Netea MG, Cavalieri D. Rizzetto L, et al. Among authors: ifrim dc. J Biol Chem. 2016 Apr 8;291(15):7961-72. doi: 10.1074/jbc.M115.699645. Epub 2016 Feb 17. J Biol Chem. 2016. PMID: 26887946 Free PMC article.