Kostenuik PJ - Search Results

1

Progressive increases in bone mass and bone strength in an ovariectomized rat model of osteoporosis after 26 weeks of treatment with a sclerostin antibody.

Li X, Niu QT, Warmington KS, Asuncion FJ, Dwyer D, Grisanti M, Han CY, Stolina M, Eschenberg MJ, Kostenuik PJ, Simonet WS, Ominsky MS, Ke HZ. Li X, et al. Among authors: kostenuik pj. Endocrinology. 2014 Dec;155(12):4785-97. doi: 10.1210/en.2013-1905. Epub 2014 Sep 26. Endocrinology. 2014. PMID: 25259718

2

Osteoprotegerin reverses osteoporosis by inhibiting endosteal osteoclasts and prevents vascular calcification by blocking a process resembling osteoclastogenesis.

Min H, Morony S, Sarosi I, Dunstan CR, Capparelli C, Scully S, Van G, Kaufman S, Kostenuik PJ, Lacey DL, Boyle WJ, Simonet WS. Min H, et al. Among authors: kostenuik pj. J Exp Med. 2000 Aug 21;192(4):463-74. doi: 10.1084/jem.192.4.463. J Exp Med. 2000. PMID: 10952716 Free PMC article.

3

Adenoviral delivery of osteoprotegerin ameliorates bone resorption in a mouse ovariectomy model of osteoporosis.

Bolon B, Carter C, Daris M, Morony S, Capparelli C, Hsieh A, Mao M, Kostenuik P, Dunstan CR, Lacey DL, Sheng JZ. Bolon B, et al. Mol Ther. 2001 Feb;3(2):197-205. doi: 10.1006/mthe.2001.0245. Mol Ther. 2001. PMID: 11237676 Free article.

4

OPG and PTH-(1-34) have additive effects on bone density and mechanical strength in osteopenic ovariectomized rats.

Kostenuik PJ, Capparelli C, Morony S, Adamu S, Shimamoto G, Shen V, Lacey DL, Dunstan CR. Kostenuik PJ, et al. Endocrinology. 2001 Oct;142(10):4295-304. doi: 10.1210/endo.142.10.8437. Endocrinology. 2001. PMID: 11564687

5

Sustained antiresorptive effects after a single treatment with human recombinant osteoprotegerin (OPG): a pharmacodynamic and pharmacokinetic analysis in rats.

Capparelli C, Morony S, Warmington K, Adamu S, Lacey D, Dunstan CR, Stouch B, Martin S, Kostenuik PJ. Capparelli C, et al. Among authors: kostenuik pj. J Bone Miner Res. 2003 May;18(5):852-8. doi: 10.1359/jbmr.2003.18.5.852. J Bone Miner Res. 2003. PMID: 12733724 Free article.

6

CD4+CD45RBHi T cell transfer induced colitis in mice is accompanied by osteopenia which is treatable with recombinant human osteoprotegerin.

Byrne FR, Morony S, Warmington K, Geng Z, Brown HL, Flores SA, Fiorino M, Yin SL, Hill D, Porkess V, Duryea D, Pretorius JK, Adamu S, Manoukian R, Danilenko DM, Sarosi I, Lacey DL, Kostenuik PJ, Senaldi G. Byrne FR, et al. Among authors: kostenuik pj. Gut. 2005 Jan;54(1):78-86. doi: 10.1136/gut.2003.035113. Gut. 2005. PMID: 15591508 Free PMC article.

7

The inhibition of RANKL causes greater suppression of bone resorption and hypercalcemia compared with bisphosphonates in two models of humoral hypercalcemia of malignancy.

Morony S, Warmington K, Adamu S, Asuncion F, Geng Z, Grisanti M, Tan HL, Capparelli C, Starnes C, Weimann B, Dunstan CR, Kostenuik PJ. Morony S, et al. Among authors: kostenuik pj. Endocrinology. 2005 Aug;146(8):3235-43. doi: 10.1210/en.2004-1583. Epub 2005 Apr 21. Endocrinology. 2005. PMID: 15845617

8

Additive bone-protective effects of anabolic treatment when used in conjunction with RANKL and tumor necrosis factor inhibition in two rat arthritis models.

Schett G, Middleton S, Bolon B, Stolina M, Brown H, Zhu L, Pretorius J, Zack DJ, Kostenuik P, Feige U. Schett G, et al. Arthritis Rheum. 2005 May;52(5):1604-11. doi: 10.1002/art.21021. Arthritis Rheum. 2005. PMID: 15880601 Free article.

9

RANKL is a marker and mediator of local and systemic bone loss in two rat models of inflammatory arthritis.

Stolina M, Adamu S, Ominsky M, Dwyer D, Asuncion F, Geng Z, Middleton S, Brown H, Pretorius J, Schett G, Bolon B, Feige U, Zack D, Kostenuik PJ. Stolina M, et al. Among authors: kostenuik pj. J Bone Miner Res. 2005 Oct;20(10):1756-65. doi: 10.1359/JBMR.050601. Epub 2005 Jun 6. J Bone Miner Res. 2005. PMID: 16160733 Free article.

10

Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia.

Li J, Sarosi I, Cattley RC, Pretorius J, Asuncion F, Grisanti M, Morony S, Adamu S, Geng Z, Qiu W, Kostenuik P, Lacey DL, Simonet WS, Bolon B, Qian X, Shalhoub V, Ominsky MS, Zhu Ke H, Li X, Richards WG. Li J, et al. Bone. 2006 Oct;39(4):754-66. doi: 10.1016/j.bone.2006.03.017. Epub 2006 May 26. Bone. 2006. PMID: 16730481

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