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Batch versus flow photochemistry: a revealing comparison of yield and productivity.
Elliott LD, Knowles JP, Koovits PJ, Maskill KG, Ralph MJ, Lejeune G, Edwards LJ, Robinson RI, Clemens IR, Cox B, Pascoe DD, Koch G, Eberle M, Berry MB, Booker-Milburn KI. Elliott LD, et al. Among authors: ralph mj. Chemistry. 2014 Nov 10;20(46):15226-32. doi: 10.1002/chem.201404347. Epub 2014 Sep 26. Chemistry. 2014. PMID: 25263341
Design and synthesis of pyridazinone-based 5-HT(2C) agonists.
Allerton CM, Andrews MD, Blagg J, Ellis D, Evrard E, Green MP, Liu KK, McMurray G, Ralph M, Sanderson V, Ward R, Watson L. Allerton CM, et al. Bioorg Med Chem Lett. 2009 Oct 1;19(19):5791-5. doi: 10.1016/j.bmcl.2009.07.136. Epub 2009 Aug 6. Bioorg Med Chem Lett. 2009. PMID: 19716297
Identification of a chemical probe for bromo and extra C-terminal bromodomain inhibition through optimization of a fragment-derived hit.
Fish PV, Filippakopoulos P, Bish G, Brennan PE, Bunnage ME, Cook AS, Federov O, Gerstenberger BS, Jones H, Knapp S, Marsden B, Nocka K, Owen DR, Philpott M, Picaud S, Primiano MJ, Ralph MJ, Sciammetta N, Trzupek JD. Fish PV, et al. Among authors: ralph mj. J Med Chem. 2012 Nov 26;55(22):9831-7. doi: 10.1021/jm3010515. Epub 2012 Nov 8. J Med Chem. 2012. PMID: 23095041 Free PMC article.