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Development of sub-nanomolar dipeptidic ligands of neuropeptide FF receptors.
Gealageas R, Schneider S, Humbert JP, Bertin I, Schmitt M, Laboureyras E, Dugave C, Mollereau C, Simonnet G, Bourguignon JJ, Simonin F, Bihel F. Gealageas R, et al. Among authors: mollereau c. Bioorg Med Chem Lett. 2012 Dec 15;22(24):7471-4. doi: 10.1016/j.bmcl.2012.10.049. Epub 2012 Oct 17. Bioorg Med Chem Lett. 2012. PMID: 23131340
Mimicking of Arginine by Functionalized N(ω)-Carbamoylated Arginine As a New Broadly Applicable Approach to Labeled Bioactive Peptides: High Affinity Angiotensin, Neuropeptide Y, Neuropeptide FF, and Neurotensin Receptor Ligands As Examples.
Keller M, Kuhn KK, Einsiedel J, Hübner H, Biselli S, Mollereau C, Wifling D, Svobodová J, Bernhardt G, Cabrele C, Vanderheyden PM, Gmeiner P, Buschauer A. Keller M, et al. Among authors: mollereau c. J Med Chem. 2016 Mar 10;59(5):1925-45. doi: 10.1021/acs.jmedchem.5b01495. Epub 2016 Feb 11. J Med Chem. 2016. PMID: 26824643
Development of a peptidomimetic antagonist of neuropeptide FF receptors for the prevention of opioid-induced hyperalgesia.
Bihel F, Humbert JP, Schneider S, Bertin I, Wagner P, Schmitt M, Laboureyras E, Petit-Demoulière B, Schneider E, Mollereau C, Simonnet G, Simonin F, Bourguignon JJ. Bihel F, et al. Among authors: mollereau c. ACS Chem Neurosci. 2015 Mar 18;6(3):438-45. doi: 10.1021/cn500219h. Epub 2015 Feb 7. ACS Chem Neurosci. 2015. PMID: 25588572
N(ω)-Carbamoylation of the Argininamide Moiety: An Avenue to Insurmountable NPY Y1 Receptor Antagonists and a Radiolabeled Selective High-Affinity Molecular Tool ([(3)H]UR-MK299) with Extended Residence Time.
Keller M, Weiss S, Hutzler C, Kuhn KK, Mollereau C, Dukorn S, Schindler L, Bernhardt G, König B, Buschauer A. Keller M, et al. Among authors: mollereau c. J Med Chem. 2015 Nov 25;58(22):8834-49. doi: 10.1021/acs.jmedchem.5b00925. Epub 2015 Nov 4. J Med Chem. 2015. PMID: 26466164
73 results