Skaar TC - Search Results

1

Genome-wide discovery of drug-dependent human liver regulatory elements.

Smith RP, Eckalbar WL, Morrissey KM, Luizon MR, Hoffmann TJ, Sun X, Jones SL, Force Aldred S, Ramamoorthy A, Desta Z, Liu Y, Skaar TC, Trinklein ND, Giacomini KM, Ahituv N. Smith RP, et al. Among authors: skaar tc. PLoS Genet. 2014 Oct 2;10(10):e1004648. doi: 10.1371/journal.pgen.1004648. eCollection 2014 Oct. PLoS Genet. 2014. PMID: 25275310 Free PMC article.

2

Sequence diversity and functional characterization of the 5'-regulatory region of human CYP2C19.

Arefayene M, Skaar TC, Zhao X, Rae JM, Tanus-Santos JE, Brinkmann U, Brehm I, Salat U, Nguyen A, Desta Z, Flockhart DA. Arefayene M, et al. Among authors: skaar tc. Pharmacogenetics. 2003 Apr;13(4):199-206. doi: 10.1097/00008571-200304000-00004. Pharmacogenetics. 2003. PMID: 12668916

3

CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment.

Jin Y, Desta Z, Stearns V, Ward B, Ho H, Lee KH, Skaar T, Storniolo AM, Li L, Araba A, Blanchard R, Nguyen A, Ullmer L, Hayden J, Lemler S, Weinshilboum RM, Rae JM, Hayes DF, Flockhart DA. Jin Y, et al. J Natl Cancer Inst. 2005 Jan 5;97(1):30-9. doi: 10.1093/jnci/dji005. J Natl Cancer Inst. 2005. PMID: 15632378

4

Endoxifen (4-hydroxy-N-desmethyl-tamoxifen) has anti-estrogenic effects in breast cancer cells with potency similar to 4-hydroxy-tamoxifen.

Lim YC, Desta Z, Flockhart DA, Skaar TC. Lim YC, et al. Among authors: skaar tc. Cancer Chemother Pharmacol. 2005 May;55(5):471-8. doi: 10.1007/s00280-004-0926-7. Epub 2005 Feb 1. Cancer Chemother Pharmacol. 2005. PMID: 15685451

5

Endoxifen, a secondary metabolite of tamoxifen, and 4-OH-tamoxifen induce similar changes in global gene expression patterns in MCF-7 breast cancer cells.

Lim YC, Li L, Desta Z, Zhao Q, Rae JM, Flockhart DA, Skaar TC. Lim YC, et al. Among authors: skaar tc. J Pharmacol Exp Ther. 2006 Aug;318(2):503-12. doi: 10.1124/jpet.105.100511. Epub 2006 May 11. J Pharmacol Exp Ther. 2006. PMID: 16690721

6

Quantitative effect of CYP2D6 genotype and inhibitors on tamoxifen metabolism: implication for optimization of breast cancer treatment.

Borges S, Desta Z, Li L, Skaar TC, Ward BA, Nguyen A, Jin Y, Storniolo AM, Nikoloff DM, Wu L, Hillman G, Hayes DF, Stearns V, Flockhart DA. Borges S, et al. Among authors: skaar tc. Clin Pharmacol Ther. 2006 Jul;80(1):61-74. doi: 10.1016/j.clpt.2006.03.013. Clin Pharmacol Ther. 2006. PMID: 16815318 Free article.

7

The pharmacogenetics research network: from SNP discovery to clinical drug response.

Giacomini KM, Brett CM, Altman RB, Benowitz NL, Dolan ME, Flockhart DA, Johnson JA, Hayes DF, Klein T, Krauss RM, Kroetz DL, McLeod HL, Nguyen AT, Ratain MJ, Relling MV, Reus V, Roden DM, Schaefer CA, Shuldiner AR, Skaar T, Tantisira K, Tyndale RF, Wang L, Weinshilboum RM, Weiss ST, Zineh I; Pharmacogenetics Research Network. Giacomini KM, et al. Clin Pharmacol Ther. 2007 Mar;81(3):328-45. doi: 10.1038/sj.clpt.6100087. Clin Pharmacol Ther. 2007. PMID: 17339863 Free PMC article. Review.

8

Estrogen receptor genotypes, menopausal status, and the lipid effects of tamoxifen.

Ntukidem NI, Nguyen AT, Stearns V, Rehman M, Schott A, Skaar T, Jin Y, Blanche P, Li L, Lemler S, Hayden J, Krauss RM, Desta Z, Flockhart DA, Hayes DF; Consortium on Breast Cancer Pharmacogenomics. Ntukidem NI, et al. Clin Pharmacol Ther. 2008 May;83(5):702-10. doi: 10.1038/sj.clpt.6100343. Epub 2007 Aug 22. Clin Pharmacol Ther. 2008. PMID: 17713466 Free PMC article. Clinical Trial.

9

A mixture model approach in gene-gene and gene-environmental interactions for binary phenotypes.

Li L, Yu M, Jason RD, Shen C, Azzouz F, McLeod HL, Borges-Gonzales S, Nguyen A, Skaar T, Desta Z, Sweeney CJ, Flockhart DA. Li L, et al. J Biopharm Stat. 2008;18(6):1150-77. doi: 10.1080/10543400802369038. J Biopharm Stat. 2008. PMID: 18991114 Free PMC article.

10

Antiestrogen pathway (aromatase inhibitor).

Desta Z, Nguyen A, Flockhart D, Skaar T, Fletcher R, Weinshilboum R, Berlin DS, Klein TE, Altman RB. Desta Z, et al. Pharmacogenet Genomics. 2009 Jul;19(7):554-5. doi: 10.1097/FPC.0b013e32832e0ec1. Pharmacogenet Genomics. 2009. PMID: 19512956 Free PMC article. No abstract available.

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