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Molecular design of the γδT cell receptor ectodomain encodes biologically fit ligand recognition in the absence of mechanosensing.
Mallis RJ, Duke-Cohan JS, Das DK, Akitsu A, Luoma AM, Banik D, Stephens HM, Tetteh PW, Castro CD, Krahnke S, Hussey RE, Lawney B, Brazin KN, Reche PA, Hwang W, Adams EJ, Lang MJ, Reinherz EL. Mallis RJ, et al. Among authors: tetteh pw. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2023050118. doi: 10.1073/pnas.2023050118. Proc Natl Acad Sci U S A. 2021. PMID: 34172580 Free PMC article.
Pre-T cell receptors topologically sample self-ligands during thymocyte β-selection.
Li X, Mizsei R, Tan K, Mallis RJ, Duke-Cohan JS, Akitsu A, Tetteh PW, Dubey A, Hwang W, Wagner G, Lang MJ, Arthanari H, Wang JH, Reinherz EL. Li X, et al. Among authors: tetteh pw. Science. 2021 Jan 8;371(6525):181-185. doi: 10.1126/science.abe0918. Epub 2020 Dec 17. Science. 2021. PMID: 33335016 Free PMC article.