Sansom DM - Search Results

1

Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations.

Schubert D, Bode C, Kenefeck R, Hou TZ, Wing JB, Kennedy A, Bulashevska A, Petersen BS, Schäffer AA, Grüning BA, Unger S, Frede N, Baumann U, Witte T, Schmidt RE, Dueckers G, Niehues T, Seneviratne S, Kanariou M, Speckmann C, Ehl S, Rensing-Ehl A, Warnatz K, Rakhmanov M, Thimme R, Hasselblatt P, Emmerich F, Cathomen T, Backofen R, Fisch P, Seidl M, May A, Schmitt-Graeff A, Ikemizu S, Salzer U, Franke A, Sakaguchi S, Walker LSK, Sansom DM, Grimbacher B. Schubert D, et al. Among authors: sansom dm. Nat Med. 2014 Dec;20(12):1410-1416. doi: 10.1038/nm.3746. Epub 2014 Oct 20. Nat Med. 2014. PMID: 25329329 Free PMC article.

2

CTLA4 gene polymorphism and autoimmunity.

Gough SC, Walker LS, Sansom DM. Gough SC, et al. Among authors: sansom dm. Immunol Rev. 2005 Apr;204:102-15. doi: 10.1111/j.0105-2896.2005.00249.x. Immunol Rev. 2005. PMID: 15790353 Review.

3

The role of CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4) in regulatory T-cell biology.

Sansom DM, Walker LS. Sansom DM, et al. Immunol Rev. 2006 Aug;212:131-48. doi: 10.1111/j.0105-2896.2006.00419.x. Immunol Rev. 2006. PMID: 16903911 Review.

4

Acquisition of suppressive function by activated human CD4+ CD25- T cells is associated with the expression of CTLA-4 not FoxP3.

Zheng Y, Manzotti CN, Burke F, Dussably L, Qureshi O, Walker LS, Sansom DM. Zheng Y, et al. Among authors: sansom dm. J Immunol. 2008 Aug 1;181(3):1683-91. doi: 10.4049/jimmunol.181.3.1683. J Immunol. 2008. PMID: 18641304 Free PMC article.

5

Ctla-4 controls regulatory T cell peripheral homeostasis and is required for suppression of pancreatic islet autoimmunity.

Schmidt EM, Wang CJ, Ryan GA, Clough LE, Qureshi OS, Goodall M, Abbas AK, Sharpe AH, Sansom DM, Walker LS. Schmidt EM, et al. Among authors: sansom dm. J Immunol. 2009 Jan 1;182(1):274-82. doi: 10.4049/jimmunol.182.1.274. J Immunol. 2009. PMID: 19109158

6

1,25-Dihydroxyvitamin D3 and IL-2 combine to inhibit T cell production of inflammatory cytokines and promote development of regulatory T cells expressing CTLA-4 and FoxP3.

Jeffery LE, Burke F, Mura M, Zheng Y, Qureshi OS, Hewison M, Walker LS, Lammas DA, Raza K, Sansom DM. Jeffery LE, et al. Among authors: sansom dm. J Immunol. 2009 Nov 1;183(9):5458-67. doi: 10.4049/jimmunol.0803217. J Immunol. 2009. PMID: 19843932 Free PMC article.

7

Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4.

Qureshi OS, Zheng Y, Nakamura K, Attridge K, Manzotti C, Schmidt EM, Baker J, Jeffery LE, Kaur S, Briggs Z, Hou TZ, Futter CE, Anderson G, Walker LS, Sansom DM. Qureshi OS, et al. Among authors: sansom dm. Science. 2011 Apr 29;332(6029):600-3. doi: 10.1126/science.1202947. Epub 2011 Apr 7. Science. 2011. PMID: 21474713 Free PMC article.

8

The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses.

Walker LS, Sansom DM. Walker LS, et al. Among authors: sansom dm. Nat Rev Immunol. 2011 Nov 25;11(12):852-63. doi: 10.1038/nri3108. Nat Rev Immunol. 2011. PMID: 22116087

9

Constitutive clathrin-mediated endocytosis of CTLA-4 persists during T cell activation.

Qureshi OS, Kaur S, Hou TZ, Jeffery LE, Poulter NS, Briggs Z, Kenefeck R, Willox AK, Royle SJ, Rappoport JZ, Sansom DM. Qureshi OS, et al. Among authors: sansom dm. J Biol Chem. 2012 Mar 16;287(12):9429-40. doi: 10.1074/jbc.M111.304329. Epub 2012 Jan 19. J Biol Chem. 2012. PMID: 22262842 Free PMC article.

10

Cutting edge: cell-extrinsic immune regulation by CTLA-4 expressed on conventional T cells.

Wang CJ, Kenefeck R, Wardzinski L, Attridge K, Manzotti C, Schmidt EM, Qureshi OS, Sansom DM, Walker LS. Wang CJ, et al. Among authors: sansom dm. J Immunol. 2012 Aug 1;189(3):1118-22. doi: 10.4049/jimmunol.1200972. Epub 2012 Jun 29. J Immunol. 2012. PMID: 22753931 Free PMC article.

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