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An intramolecular lock facilitates folding and stabilizes the tertiary structure of Streptococcus mutans adhesin P1.
Proc Natl Acad Sci U S A. 2014 Nov 4;111(44):15746-51. doi: 10.1073/pnas.1413018111. Epub 2014 Oct 20.
Proc Natl Acad Sci U S A. 2014.
PMID: 25331888
Free PMC article.
An intramolecular interaction involving the N terminus of a streptococcal adhesin affects its conformation and adhesive function.
Heim KP, Crowley PJ, Brady LJ.
Heim KP, et al.
J Biol Chem. 2013 May 10;288(19):13762-74. doi: 10.1074/jbc.M113.459974. Epub 2013 Mar 28.
J Biol Chem. 2013.
PMID: 23539625
Free PMC article.
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Alterations in immunodominance of Streptococcus mutans AgI/II: lessons learned from immunomodulatory antibodies.
Robinette RA, Heim KP, Oli MW, Crowley PJ, McArthur WP, Brady LJ.
Robinette RA, et al. Among authors: heim kp.
Vaccine. 2014 Jan 9;32(3):375-82. doi: 10.1016/j.vaccine.2013.11.023. Epub 2013 Nov 16.
Vaccine. 2014.
PMID: 24252705
Free PMC article.
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Identification of a supramolecular functional architecture of Streptococcus mutans adhesin P1 on the bacterial cell surface.
Heim KP, Sullan RM, Crowley PJ, El-Kirat-Chatel S, Beaussart A, Tang W, Besingi R, Dufrene YF, Brady LJ.
Heim KP, et al.
J Biol Chem. 2015 Apr 3;290(14):9002-19. doi: 10.1074/jbc.M114.626663. Epub 2015 Feb 9.
J Biol Chem. 2015.
PMID: 25666624
Free PMC article.
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Functional amyloid formation by Streptococcus mutans.
Oli MW, Otoo HN, Crowley PJ, Heim KP, Nascimento MM, Ramsook CB, Lipke PN, Brady LJ.
Oli MW, et al. Among authors: heim kp.
Microbiology (Reading). 2012 Dec;158(Pt 12):2903-2916. doi: 10.1099/mic.0.060855-0. Epub 2012 Oct 18.
Microbiology (Reading). 2012.
PMID: 23082034
Free PMC article.
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Streptococcus mutans extracellular DNA is upregulated during growth in biofilms, actively released via membrane vesicles, and influenced by components of the protein secretion machinery.
Liao S, Klein MI, Heim KP, Fan Y, Bitoun JP, Ahn SJ, Burne RA, Koo H, Brady LJ, Wen ZT.
Liao S, et al. Among authors: heim kp.
J Bacteriol. 2014 Jul;196(13):2355-66. doi: 10.1128/JB.01493-14. Epub 2014 Apr 18.
J Bacteriol. 2014.
PMID: 24748612
Free PMC article.
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Prefusion structure of human cytomegalovirus glycoprotein B and structural basis for membrane fusion.
Liu Y, Heim KP, Che Y, Chi X, Qiu X, Han S, Dormitzer PR, Yang X.
Liu Y, et al. Among authors: heim kp.
Sci Adv. 2021 Mar 5;7(10):eabf3178. doi: 10.1126/sciadv.abf3178. Print 2021 Mar.
Sci Adv. 2021.
PMID: 33674318
Free PMC article.
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