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Genetic Variability Overrides the Impact of Parental Cell Type and Determines iPSC Differentiation Potential.
Kyttälä A, Moraghebi R, Valensisi C, Kettunen J, Andrus C, Pasumarthy KK, Nakanishi M, Nishimura K, Ohtaka M, Weltner J, Van Handel B, Parkkonen O, Sinisalo J, Jalanko A, Hawkins RD, Woods NB, Otonkoski T, Trokovic R. Kyttälä A, et al. Stem Cell Reports. 2016 Feb 9;6(2):200-12. doi: 10.1016/j.stemcr.2015.12.009. Epub 2016 Jan 14. Stem Cell Reports. 2016. PMID: 26777058 Free PMC article.
CRISPR activation enables high-fidelity reprogramming into human pluripotent stem cells.
Sokka J, Yoshihara M, Kvist J, Laiho L, Warren A, Stadelmann C, Jouhilahti EM, Kilpinen H, Balboa D, Katayama S, Kyttälä A, Kere J, Otonkoski T, Weltner J, Trokovic R. Sokka J, et al. Among authors: kyttala a. Stem Cell Reports. 2022 Feb 8;17(2):413-426. doi: 10.1016/j.stemcr.2021.12.017. Epub 2022 Jan 20. Stem Cell Reports. 2022. PMID: 35063129 Free PMC article.
AP-1 and AP-3 facilitate lysosomal targeting of Batten disease protein CLN3 via its dileucine motif.
Kyttälä A, Yliannala K, Schu P, Jalanko A, Luzio JP. Kyttälä A, et al. J Biol Chem. 2005 Mar 18;280(11):10277-83. doi: 10.1074/jbc.M411862200. Epub 2004 Dec 13. J Biol Chem. 2005. PMID: 15598649 Free article.
CLN3 is a transmembrane protein with a predominant localization in lysosomes in non-neuronal cells but is also found in endosomes and the synaptic region in neuronal cells. ...We have recently reported that the lysosomal targeting of CLN3 is facilitated by two targe …
CLN3 is a transmembrane protein with a predominant localization in lysosomes in non-neuronal cells but is also found in endoso …
33 results