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N-glycolylneuraminic acid xenoantigen contamination of human embryonic and mesenchymal stem cells is substantially reversible.
Heiskanen A, Satomaa T, Tiitinen S, Laitinen A, Mannelin S, Impola U, Mikkola M, Olsson C, Miller-Podraza H, Blomqvist M, Olonen A, Salo H, Lehenkari P, Tuuri T, Otonkoski T, Natunen J, Saarinen J, Laine J. Heiskanen A, et al. Among authors: otonkoski t. Stem Cells. 2007 Jan;25(1):197-202. doi: 10.1634/stemcells.2006-0444. Epub 2006 Sep 28. Stem Cells. 2007. PMID: 17008421
A defined and xeno-free culture method enabling the establishment of clinical-grade human embryonic, induced pluripotent and adipose stem cells.
Rajala K, Lindroos B, Hussein SM, Lappalainen RS, Pekkanen-Mattila M, Inzunza J, Rozell B, Miettinen S, Narkilahti S, Kerkelä E, Aalto-Setälä K, Otonkoski T, Suuronen R, Hovatta O, Skottman H. Rajala K, et al. Among authors: otonkoski t. PLoS One. 2010 Apr 19;5(4):e10246. doi: 10.1371/journal.pone.0010246. PLoS One. 2010. PMID: 20419109 Free PMC article.
Copy number variation and selection during reprogramming to pluripotency.
Hussein SM, Batada NN, Vuoristo S, Ching RW, Autio R, Närvä E, Ng S, Sourour M, Hämäläinen R, Olsson C, Lundin K, Mikkola M, Trokovic R, Peitz M, Brüstle O, Bazett-Jones DP, Alitalo K, Lahesmaa R, Nagy A, Otonkoski T. Hussein SM, et al. Among authors: otonkoski t. Nature. 2011 Mar 3;471(7336):58-62. doi: 10.1038/nature09871. Nature. 2011. PMID: 21368824
High-throughput karyotyping of human pluripotent stem cells.
Lund RJ, Nikula T, Rahkonen N, Närvä E, Baker D, Harrison N, Andrews P, Otonkoski T, Lahesmaa R. Lund RJ, et al. Among authors: otonkoski t. Stem Cell Res. 2012 Nov;9(3):192-5. doi: 10.1016/j.scr.2012.06.008. Epub 2012 Jul 11. Stem Cell Res. 2012. PMID: 22877823 Free PMC article.
Comparative analysis of targeted differentiation of human induced pluripotent stem cells (hiPSCs) and human embryonic stem cells reveals variability associated with incomplete transgene silencing in retrovirally derived hiPSC lines.
Toivonen S, Ojala M, Hyysalo A, Ilmarinen T, Rajala K, Pekkanen-Mattila M, Äänismaa R, Lundin K, Palgi J, Weltner J, Trokovic R, Silvennoinen O, Skottman H, Narkilahti S, Aalto-Setälä K, Otonkoski T. Toivonen S, et al. Among authors: otonkoski t. Stem Cells Transl Med. 2013 Feb;2(2):83-93. doi: 10.5966/sctm.2012-0047. Epub 2013 Jan 22. Stem Cells Transl Med. 2013. PMID: 23341440 Free PMC article.
Activin A and Wnt-dependent specification of human definitive endoderm cells.
Toivonen S, Lundin K, Balboa D, Ustinov J, Tamminen K, Palgi J, Trokovic R, Tuuri T, Otonkoski T. Toivonen S, et al. Among authors: otonkoski t. Exp Cell Res. 2013 Oct 15;319(17):2535-44. doi: 10.1016/j.yexcr.2013.07.007. Epub 2013 Aug 14. Exp Cell Res. 2013. PMID: 23954819
217 results