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Protective role of plant sterol and stanol esters in liver inflammation: insights from mice and humans.
Plat J, Hendrikx T, Bieghs V, Jeurissen ML, Walenbergh SM, van Gorp PJ, De Smet E, Konings M, Vreugdenhil AC, Guichot YD, Rensen SS, Buurman WA, Greve JW, Lütjohann D, Mensink RP, Shiri-Sverdlov R. Plat J, et al. Among authors: guichot yd. PLoS One. 2014 Oct 30;9(10):e110758. doi: 10.1371/journal.pone.0110758. eCollection 2014. PLoS One. 2014. PMID: 25356831 Free PMC article.
The cholesterol derivative 27-hydroxycholesterol reduces steatohepatitis in mice.
Bieghs V, Hendrikx T, van Gorp PJ, Verheyen F, Guichot YD, Walenbergh SM, Jeurissen ML, Gijbels M, Rensen SS, Bast A, Plat J, Kalhan SC, Koek GH, Leitersdorf E, Hofker MH, Lütjohann D, Shiri-Sverdlov R. Bieghs V, et al. Among authors: guichot yd. Gastroenterology. 2013 Jan;144(1):167-178.e1. doi: 10.1053/j.gastro.2012.09.062. Epub 2012 Oct 3. Gastroenterology. 2013. PMID: 23041327
Hematopoietic overexpression of Cyp27a1 reduces hepatic inflammation independently of 27-hydroxycholesterol levels in Ldlr(-/-) mice.
Hendrikx T, Jeurissen ML, Bieghs V, Walenbergh SM, van Gorp PJ, Verheyen F, Houben T, Guichot YD, Gijbels MJ, Leitersdorf E, Hofker MH, Lütjohann D, Shiri-Sverdlov R. Hendrikx T, et al. Among authors: guichot yd. J Hepatol. 2015 Feb;62(2):430-6. doi: 10.1016/j.jhep.2014.09.027. Epub 2014 Oct 2. J Hepatol. 2015. PMID: 25281859