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Insulin Receptor and the Kidney: Nephrocalcinosis in Patients with Recessive INSR Mutations.
Simpkin A, Cochran E, Cameron F, Dattani M, de Bock M, Dunger DB, Forsander G, Guran T, Harris J, Isaac I, Hussain K, Kleta R, Peters C, Tasic V, Williams R, Yap Kok Peng F, O''Rahilly S, Gorden P, Semple RK, Bockenhauer D. Simpkin A, et al. Among authors: semple rk. Nephron Physiol. 2014;128(3-4):55-61. doi: 10.1159/000366225. Epub 2014 Oct 24. Nephron Physiol. 2014. PMID: 25358339 Free PMC article.
IGF-I treatment of insulin resistance.
McDonald A, Williams RM, Regan FM, Semple RK, Dunger DB. McDonald A, et al. Among authors: semple rk. Eur J Endocrinol. 2007 Aug;157 Suppl 1:S51-6. doi: 10.1530/EJE-07-0271. Eur J Endocrinol. 2007. PMID: 17785698 Review.
Treatment with recombinant human insulin-like growth factor (rhIGF)-I/rhIGF binding protein-3 complex improves metabolic control in subjects with severe insulin resistance.
Regan FM, Williams RM, McDonald A, Umpleby AM, Acerini CL, O'Rahilly S, Hovorka R, Semple RK, Dunger DB. Regan FM, et al. Among authors: semple rk. J Clin Endocrinol Metab. 2010 May;95(5):2113-22. doi: 10.1210/jc.2009-2088. Epub 2010 Mar 16. J Clin Endocrinol Metab. 2010. PMID: 20233784
Founder effect in the Horn of Africa for an insulin receptor mutation that may impair receptor recycling.
Raffan E, Soos MA, Rocha N, Tuthill A, Thomsen AR, Hyden CS, Gregory JW, Hindmarsh P, Dattani M, Cochran E, Al Kaabi J, Gorden P, Barroso I, Morling N, O'Rahilly S, Semple RK. Raffan E, et al. Among authors: semple rk. Diabetologia. 2011 May;54(5):1057-65. doi: 10.1007/s00125-011-2066-z. Epub 2011 Feb 12. Diabetologia. 2011. PMID: 21318406 Free PMC article.
Genetic syndromes of severe insulin resistance.
Semple RK, Savage DB, Cochran EK, Gorden P, O'Rahilly S. Semple RK, et al. Endocr Rev. 2011 Aug;32(4):498-514. doi: 10.1210/er.2010-0020. Epub 2011 May 2. Endocr Rev. 2011. PMID: 21536711 Review.
222 results