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Optimization of Hydroxyethylamine Transition State Isosteres as Aspartic Protease Inhibitors by Exploiting Conformational Preferences.
Bueno AB, Agejas J, Broughton H, Dally R, Durham TB, Espinosa JF, González R, Hahn PJ, Marcos A, Rodríguez R, Sanz G, Soriano JF, Timm D, Vidal P, Yang HC, McCarthy JR. Bueno AB, et al. Among authors: hahn pj. J Med Chem. 2017 Dec 14;60(23):9807-9820. doi: 10.1021/acs.jmedchem.7b01304. Epub 2017 Nov 28. J Med Chem. 2017. PMID: 29088532
Perampanel, an antagonist of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors, for the treatment of epilepsy: studies in human epileptic brain and nonepileptic brain and in rodent models.
Zwart R, Sher E, Ping X, Jin X, Sims JR Jr, Chappell AS, Gleason SD, Hahn PJ, Gardinier K, Gernert DL, Hobbs J, Smith JL, Valli SN, Witkin JM. Zwart R, et al. Among authors: hahn pj. J Pharmacol Exp Ther. 2014 Oct;351(1):124-33. doi: 10.1124/jpet.114.212779. Epub 2014 Jul 15. J Pharmacol Exp Ther. 2014. PMID: 25027316
Pallidal burst activity during therapeutic deep brain stimulation.
Hahn PJ, Russo GS, Hashimoto T, Miocinovic S, Xu W, McIntyre CC, Vitek JL. Hahn PJ, et al. Exp Neurol. 2008 May;211(1):243-51. doi: 10.1016/j.expneurol.2008.01.032. Epub 2008 Feb 20. Exp Neurol. 2008. PMID: 18355810 Free PMC article.
43 results