Westcott PM - Search Results

1

The mutational landscapes of genetic and chemical models of Kras-driven lung cancer.

Westcott PM, Halliwill KD, To MD, Rashid M, Rust AG, Keane TM, Delrosario R, Jen KY, Gurley KE, Kemp CJ, Fredlund E, Quigley DA, Adams DJ, Balmain A. Westcott PM, et al. Nature. 2015 Jan 22;517(7535):489-92. doi: 10.1038/nature13898. Epub 2014 Nov 2. Nature. 2015. PMID: 25363767 Free PMC article.

2

The genetics and biology of KRAS in lung cancer.

Westcott PM, To MD. Westcott PM, et al. Chin J Cancer. 2013 Feb;32(2):63-70. doi: 10.5732/cjc.012.10098. Epub 2012 Jul 2. Chin J Cancer. 2013. PMID: 22776234 Free PMC article. Review.

3

Interactions between wild-type and mutant Ras genes in lung and skin carcinogenesis.

To MD, Rosario RD, Westcott PM, Banta KL, Balmain A. To MD, et al. Among authors: westcott pm. Oncogene. 2013 Aug 22;32(34):4028-33. doi: 10.1038/onc.2012.404. Epub 2012 Sep 3. Oncogene. 2013. PMID: 22945650 Free PMC article.

4

Targeting KRAS4A splicing through the RBM39/DCAF15 pathway inhibits cancer stem cells.

Chen WC, To MD, Westcott PMK, Delrosario R, Kim IJ, Philips M, Tran Q, Bollam SR, Goodarzi H, Bayani N, Mirzoeva O, Balmain A. Chen WC, et al. Nat Commun. 2021 Jul 13;12(1):4288. doi: 10.1038/s41467-021-24498-7. Nat Commun. 2021. PMID: 34257283 Free PMC article.

5

Urinary detection of lung cancer in mice via noninvasive pulmonary protease profiling.

Kirkpatrick JD, Warren AD, Soleimany AP, Westcott PMK, Voog JC, Martin-Alonso C, Fleming HE, Tammela T, Jacks T, Bhatia SN. Kirkpatrick JD, et al. Sci Transl Med. 2020 Apr 1;12(537):eaaw0262. doi: 10.1126/scitranslmed.aaw0262. Sci Transl Med. 2020. PMID: 32238573 Free PMC article.

6

Keap1 mutation renders lung adenocarcinomas dependent on Slc33a1.

Romero R, Sánchez-Rivera FJ, Westcott PMK, Mercer KL, Bhutkar A, Muir A, González Robles TJ, Lamboy Rodríguez S, Liao LZ, Ng SR, Li L, Colón CI, Naranjo S, Beytagh MC, Lewis CA, Hsu PP, Bronson RT, Vander Heiden MG, Jacks T. Romero R, et al. Nat Cancer. 2020 Jun;1(6):589-602. doi: 10.1038/s43018-020-0071-1. Epub 2020 Jun 8. Nat Cancer. 2020. PMID: 34414377 Free PMC article.

7

Low neoantigen expression and poor T-cell priming underlie early immune escape in colorectal cancer.

Westcott PMK, Sacks NJ, Schenkel JM, Ely ZA, Smith O, Hauck H, Jaeger AM, Zhang D, Backlund CM, Beytagh MC, Patten JJ, Elbashir R, Eng G, Irvine DJ, Yilmaz OH, Jacks T. Westcott PMK, et al. Nat Cancer. 2021 Oct;2(10):1071-1085. doi: 10.1038/s43018-021-00247-z. Epub 2021 Sep 30. Nat Cancer. 2021. PMID: 34738089 Free PMC article.

8

Deciphering the immunopeptidome in vivo reveals new tumour antigens.

Jaeger AM, Stopfer LE, Ahn R, Sanders EA, Sandel DA, Freed-Pastor WA, Rideout WM 3rd, Naranjo S, Fessenden T, Nguyen KB, Winter PS, Kohn RE, Westcott PMK, Schenkel JM, Shanahan SL, Shalek AK, Spranger S, White FM, Jacks T. Jaeger AM, et al. Among authors: westcott pmk. Nature. 2022 Jul;607(7917):149-155. doi: 10.1038/s41586-022-04839-2. Epub 2022 Jun 15. Nature. 2022. PMID: 35705813 Free PMC article.

9

Modeling diverse genetic subtypes of lung adenocarcinoma with a next-generation alveolar type 2 organoid platform.

Naranjo S, Cabana CM, LaFave LM, Romero R, Shanahan SL, Bhutkar A, Westcott PMK, Schenkel JM, Ghosh A, Liao LZ, Del Priore I, Yang D, Jacks T. Naranjo S, et al. Among authors: westcott pmk. Genes Dev. 2022 Aug 1;36(15-16):936-949. doi: 10.1101/gad.349659.122. Epub 2022 Sep 29. Genes Dev. 2022. PMID: 36175034 Free PMC article.

10

A prime editor mouse to model a broad spectrum of somatic mutations in vivo.

Ely ZA, Mathey-Andrews N, Naranjo S, Gould SI, Mercer KL, Newby GA, Cabana CM, Rideout WM 3rd, Jaramillo GC, Khirallah JM, Holland K, Randolph PB, Freed-Pastor WA, Davis JR, Kulstad Z, Westcott PMK, Lin L, Anzalone AV, Horton BL, Pattada NB, Shanahan SL, Ye Z, Spranger S, Xu Q, Sánchez-Rivera FJ, Liu DR, Jacks T. Ely ZA, et al. Among authors: westcott pmk. Nat Biotechnol. 2024 Mar;42(3):424-436. doi: 10.1038/s41587-023-01783-y. Epub 2023 May 11. Nat Biotechnol. 2024. PMID: 37169967

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