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OX40- and CD27-mediated costimulation synergizes with anti-PD-L1 blockade by forcing exhausted CD8+ T cells to exit quiescence.
Buchan S, Manzo T, Flutter B, Rogel A, Edwards N, Zhang L, Sivakumaran S, Ghorashian S, Carpenter B, Bennett C, Freeman GJ, Sykes M, Croft M, Al-Shamkhani A, Chakraverty R. Buchan S, et al. Among authors: rogel a. J Immunol. 2015 Jan 1;194(1):125-133. doi: 10.4049/jimmunol.1401644. Epub 2014 Nov 17. J Immunol. 2015. PMID: 25404365 Free PMC article.
PD-1 Blockade and CD27 Stimulation Activate Distinct Transcriptional Programs That Synergize for CD8+ T-Cell-Driven Antitumor Immunity.
Buchan SL, Fallatah M, Thirdborough SM, Taraban VY, Rogel A, Thomas LJ, Penfold CA, He LZ, Curran MA, Keler T, Al-Shamkhani A. Buchan SL, et al. Among authors: rogel a. Clin Cancer Res. 2018 May 15;24(10):2383-2394. doi: 10.1158/1078-0432.CCR-17-3057. Epub 2018 Mar 7. Clin Cancer Res. 2018. PMID: 29514845 Free PMC article.
Antibodies to Costimulatory Receptor 4-1BB Enhance Anti-tumor Immunity via T Regulatory Cell Depletion and Promotion of CD8 T Cell Effector Function.
Buchan SL, Dou L, Remer M, Booth SG, Dunn SN, Lai C, Semmrich M, Teige I, Mårtensson L, Penfold CA, Chan HTC, Willoughby JE, Mockridge CI, Dahal LN, Cleary KLS, James S, Rogel A, Kannisto P, Jernetz M, Williams EL, Healy E, Verbeek JS, Johnson PWM, Frendéus B, Cragg MS, Glennie MJ, Gray JC, Al-Shamkhani A, Beers SA. Buchan SL, et al. Among authors: rogel a. Immunity. 2018 Nov 20;49(5):958-970.e7. doi: 10.1016/j.immuni.2018.09.014. Epub 2018 Nov 13. Immunity. 2018. PMID: 30446386 Free article.
Fcγ receptor binding is required for maximal immunostimulation by CD70-Fc.
Dadas O, Allen JD, Buchan SL, Kim J, Chan HTC, Mockridge CI, Duriez PJ, Rogel A, Crispin M, Al-Shamkhani A. Dadas O, et al. Among authors: rogel a. Front Immunol. 2023 Oct 27;14:1252274. doi: 10.3389/fimmu.2023.1252274. eCollection 2023. Front Immunol. 2023. PMID: 37965342 Free PMC article.
Clarification Regarding Breast Cancer Stage in France.
Molinié F, Lafay L, Rogel A. Molinié F, et al. Among authors: rogel a. JAMA Oncol. 2024 Apr 25. doi: 10.1001/jamaoncol.2024.0668. Online ahead of print. JAMA Oncol. 2024. PMID: 38662355 No abstract available.
81 results