Thomas H - Search Results

1

Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche.

Davis H, Irshad S, Bansal M, Rafferty H, Boitsova T, Bardella C, Jaeger E, Lewis A, Freeman-Mills L, Giner FC, Rodenas-Cuadrado P, Mallappa S, Clark S, Thomas H, Jeffery R, Poulsom R, Rodriguez-Justo M, Novelli M, Chetty R, Silver A, Sansom OJ, Greten FR, Wang LM, East JE, Tomlinson I, Leedham SJ. Davis H, et al. Among authors: thomas h. Nat Med. 2015 Jan;21(1):62-70. doi: 10.1038/nm.3750. Epub 2014 Dec 1. Nat Med. 2015. PMID: 25419707 Free PMC article.

2

Clinical and molecular features of the hereditary mixed polyposis syndrome.

Whitelaw SC, Murday VA, Tomlinson IP, Thomas HJ, Cottrell S, Ginsberg A, Bukofzer S, Hodgson SV, Skudowitz RB, Jass JR, Talbot IC, Northover JM, Bodmer WF, Solomon E. Whitelaw SC, et al. Among authors: thomas hj. Gastroenterology. 1997 Feb;112(2):327-34. doi: 10.1053/gast.1997.v112.pm9024286. Gastroenterology. 1997. PMID: 9024286

3

The APC variants I1307K and E1317Q are associated with colorectal tumors, but not always with a family history.

Frayling IM, Beck NE, Ilyas M, Dove-Edwin I, Goodman P, Pack K, Bell JA, Williams CB, Hodgson SV, Thomas HJ, Talbot IC, Bodmer WF, Tomlinson IP. Frayling IM, et al. Among authors: thomas hj. Proc Natl Acad Sci U S A. 1998 Sep 1;95(18):10722-7. doi: 10.1073/pnas.95.18.10722. Proc Natl Acad Sci U S A. 1998. PMID: 9724771 Free PMC article.

4

Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH.

Sieber OM, Lipton L, Crabtree M, Heinimann K, Fidalgo P, Phillips RK, Bisgaard ML, Orntoft TF, Aaltonen LA, Hodgson SV, Thomas HJ, Tomlinson IP. Sieber OM, et al. N Engl J Med. 2003 Feb 27;348(9):791-9. doi: 10.1056/NEJMoa025283. N Engl J Med. 2003. PMID: 12606733 Free article.

5

Germline mutations but not somatic changes at the MYH locus contribute to the pathogenesis of unselected colorectal cancers.

Halford SE, Rowan AJ, Lipton L, Sieber OM, Pack K, Thomas HJ, Hodgson SV, Bodmer WF, Tomlinson IP. Halford SE, et al. Am J Pathol. 2003 May;162(5):1545-8. doi: 10.1016/S0002-9440(10)64288-5. Am J Pathol. 2003. PMID: 12707038 Free PMC article.

6

Contribution of the CHEK2 1100delC variant to risk of multiple colorectal adenoma and carcinoma.

Lipton L, Fleischmann C, Sieber OM, Thomas HJ, Hodgson SV, Tomlinson IP, Houlston RS. Lipton L, et al. Cancer Lett. 2003 Oct 28;200(2):149-52. doi: 10.1016/s0304-3835(03)00391-4. Cancer Lett. 2003. PMID: 14568168

7

Apparent Mendelian inheritance of breast and colorectal cancer: chance, genetic heterogeneity or a new gene?

Lipton L, Thomas HJ, Eeles RA, Houlston RS, Longmuir M, Davison R, Hodgson SV, Murday VA, Norbury CG, Taylor C, Tomlinson IP. Lipton L, et al. Among authors: thomas hj. Fam Cancer. 2001;1(3-4):189-95. doi: 10.1023/a:1021101014264. Fam Cancer. 2001. PMID: 14574178 Review.

8

Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway.

Lipton L, Halford SE, Johnson V, Novelli MR, Jones A, Cummings C, Barclay E, Sieber O, Sadat A, Bisgaard ML, Hodgson SV, Aaltonen LA, Thomas HJ, Tomlinson IP. Lipton L, et al. Cancer Res. 2003 Nov 15;63(22):7595-9. Cancer Res. 2003. PMID: 14633673

9

Analysis of somatic molecular changes, clinicopathological features, family history, and germline mutations in colorectal cancer families: evidence for efficient diagnosis of HNPCC and for the existence of distinct groups of non-HNPCC families.

Johnson V, Lipton LR, Cummings C, Eftekhar Sadat AT, Izatt L, Hodgson SV, Talbot IC, Thomas HJ, Silver AJ, Tomlinson IP. Johnson V, et al. Among authors: thomas hj. J Med Genet. 2005 Oct;42(10):756-62. doi: 10.1136/jmg.2005.031245. Epub 2005 Mar 23. J Med Genet. 2005. PMID: 15788729 Free PMC article.

10

Evidence for an association between compound heterozygosity for germ line mutations in the hemochromatosis (HFE) gene and increased risk of colorectal cancer.

Robinson JP, Johnson VL, Rogers PA, Houlston RS, Maher ER, Bishop DT, Evans DG, Thomas HJ, Tomlinson IP, Silver AR. Robinson JP, et al. Cancer Epidemiol Biomarkers Prev. 2005 Jun;14(6):1460-3. doi: 10.1158/1055-9965.EPI-04-0672. Cancer Epidemiol Biomarkers Prev. 2005. PMID: 15941956

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