Zhang Z - Search Results

1

O-GlcNAc-modification of SNAP-29 regulates autophagosome maturation.

Guo B, Liang Q, Li L, Hu Z, Wu F, Zhang P, Ma Y, Zhao B, Kovács AL, Zhang Z, Feng D, Chen S, Zhang H. Guo B, et al. Among authors: zhang p, zhang z, zhang h. Nat Cell Biol. 2014 Dec;16(12):1215-26. doi: 10.1038/ncb3066. Epub 2014 Nov 24. Nat Cell Biol. 2014. PMID: 25419848

2

A Small Molecule That Protects the Integrity of the Electron Transfer Chain Blocks the Mitochondrial Apoptotic Pathway.

Jiang X, Li L, Ying Z, Pan C, Huang S, Li L, Dai M, Yan B, Li M, Jiang H, Chen S, Zhang Z, Wang X. Jiang X, et al. Among authors: zhang z. Mol Cell. 2016 Jul 21;63(2):229-239. doi: 10.1016/j.molcel.2016.06.016. Mol Cell. 2016. PMID: 27447985 Free article.

3

Discovery of a New Class of Uracil Derivatives as Potential Mixed Lineage Kinase Domain-like Protein (MLKL) Inhibitors.

Cui B, Yan B, Wang K, Li L, Chen S, Zhang Z. Cui B, et al. Among authors: zhang z. J Med Chem. 2022 Oct 13;65(19):12747-12780. doi: 10.1021/acs.jmedchem.2c00548. Epub 2022 Sep 22. J Med Chem. 2022. PMID: 36136378

4

Focusing on probe-modified peptides: a quick and effective method for target identification.

Sun H, Ren Y, Hou W, Li L, Zeng F, Li S, Ma Y, Liu X, Chen S, Zhang Z. Sun H, et al. Among authors: zhang z. Chem Commun (Camb). 2016 Aug 11;52(67):10225-8. doi: 10.1039/c6cc04030f. Chem Commun (Camb). 2016. PMID: 27443632

5

Discovery of a new class of highly potent necroptosis inhibitors targeting the mixed lineage kinase domain-like protein.

Yan B, Liu L, Huang S, Ren Y, Wang H, Yao Z, Li L, Chen S, Wang X, Zhang Z. Yan B, et al. Among authors: zhang z. Chem Commun (Camb). 2017 Mar 28;53(26):3637-3640. doi: 10.1039/c7cc00667e. Chem Commun (Camb). 2017. PMID: 28267172

6

Identification and Optimization of Novel Cathepsin C Inhibitors Derived from EGFR Inhibitors.

Hou W, Sun H, Ma Y, Liu C, Zhang Z. Hou W, et al. Among authors: zhang z. J Med Chem. 2019 Jun 27;62(12):5901-5919. doi: 10.1021/acs.jmedchem.9b00631. Epub 2019 Jun 17. J Med Chem. 2019. PMID: 31145622

7

Activity-based protein profiling reveals GSTO1 as the covalent target of piperlongumine and a promising target for combination therapy for cancer.

Li L , Zhao Y , Cao R , Li L , Cai G , Li J , Qi X , Chen S , Zhang Z . Li L , et al. Among authors: zhang z. Chem Commun (Camb). 2019 Apr 9;55(30):4407-4410. doi: 10.1039/c9cc00917e. Chem Commun (Camb). 2019. PMID: 30916079

8

A small molecule protects mitochondrial integrity by inhibiting mTOR activity.

Cao R, Li L, Ying Z, Cao Z, Ma Y, Mao X, Li J, Qi X, Zhang Z, Wang X. Cao R, et al. Among authors: zhang z. Proc Natl Acad Sci U S A. 2019 Nov 12;116(46):23332-23338. doi: 10.1073/pnas.1911246116. Epub 2019 Oct 25. Proc Natl Acad Sci U S A. 2019. PMID: 31653761 Free PMC article.

9

Discovery of a Highly Potent, Selective, and Metabolically Stable Inhibitor of Receptor-Interacting Protein 1 (RIP1) for the Treatment of Systemic Inflammatory Response Syndrome.

Ren Y, Su Y, Sun L, He S, Meng L, Liao D, Liu X, Ma Y, Liu C, Li S, Ruan H, Lei X, Wang X, Zhang Z. Ren Y, et al. Among authors: zhang z. J Med Chem. 2017 Feb 9;60(3):972-986. doi: 10.1021/acs.jmedchem.6b01196. Epub 2017 Jan 5. J Med Chem. 2017. PMID: 27992216

10

Identification of entacapone as a chemical inhibitor of FTO mediating metabolic regulation through FOXO1.

Peng S, Xiao W, Ju D, Sun B, Hou N, Liu Q, Wang Y, Zhao H, Gao C, Zhang S, Cao R, Li P, Huang H, Ma Y, Wang Y, Lai W, Ma Z, Zhang W, Huang S, Wang H, Zhang Z, Zhao L, Cai T, Zhao YL, Wang F, Nie Y, Zhi G, Yang YG, Zhang EE, Huang N. Peng S, et al. Among authors: zhang s, zhang w, zhang z, zhang ee. Sci Transl Med. 2019 Apr 17;11(488):eaau7116. doi: 10.1126/scitranslmed.aau7116. Sci Transl Med. 2019. PMID: 30996080

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