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Akt inhibition enhances expansion of potent tumor-specific lymphocytes with memory cell characteristics.
Crompton JG, Sukumar M, Roychoudhuri R, Clever D, Gros A, Eil RL, Tran E, Hanada K, Yu Z, Palmer DC, Kerkar SP, Michalek RD, Upham T, Leonardi A, Acquavella N, Wang E, Marincola FM, Gattinoni L, Muranski P, Sundrud MS, Klebanoff CA, Rosenberg SA, Fearon DT, Restifo NP. Crompton JG, et al. Among authors: sundrud ms. Cancer Res. 2015 Jan 15;75(2):296-305. doi: 10.1158/0008-5472.CAN-14-2277. Epub 2014 Nov 28. Cancer Res. 2015. PMID: 25432172 Free PMC article.
Targeting Th17 cells in autoimmune diseases.
Yang J, Sundrud MS, Skepner J, Yamagata T. Yang J, et al. Among authors: sundrud ms. Trends Pharmacol Sci. 2014 Oct;35(10):493-500. doi: 10.1016/j.tips.2014.07.006. Epub 2014 Aug 14. Trends Pharmacol Sci. 2014. PMID: 25131183 Review.
The Xenobiotic Transporter Mdr1 Enforces T Cell Homeostasis in the Presence of Intestinal Bile Acids.
Cao W, Kayama H, Chen ML, Delmas A, Sun A, Kim SY, Rangarajan ES, McKevitt K, Beck AP, Jackson CB, Crynen G, Oikonomopoulos A, Lacey PN, Martinez GJ, Izard T, Lorenz RG, Rodriguez-Palacios A, Cominelli F, Abreu MT, Hommes DW, Koralov SB, Takeda K, Sundrud MS. Cao W, et al. Among authors: sundrud ms. Immunity. 2017 Dec 19;47(6):1182-1196.e10. doi: 10.1016/j.immuni.2017.11.012. Immunity. 2017. PMID: 29262351 Free PMC article.
CAR directs T cell adaptation to bile acids in the small intestine.
Chen ML, Huang X, Wang H, Hegner C, Liu Y, Shang J, Eliason A, Diao H, Park H, Frey B, Wang G, Mosure SA, Solt LA, Kojetin DJ, Rodriguez-Palacios A, Schady DA, Weaver CT, Pipkin ME, Moore DD, Sundrud MS. Chen ML, et al. Among authors: sundrud ms. Nature. 2021 May;593(7857):147-151. doi: 10.1038/s41586-021-03421-6. Epub 2021 Apr 7. Nature. 2021. PMID: 33828301 Free PMC article.
48 results