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A rare functional noncoding variant at the GWAS-implicated MIR137/MIR2682 locus might confer risk to schizophrenia and bipolar disorder.
Am J Hum Genet. 2014 Dec 4;95(6):744-53. doi: 10.1016/j.ajhg.2014.11.001. Epub 2014 Nov 26.
Am J Hum Genet. 2014.
PMID: 25434007
Free PMC article.
Transcriptome outlier analysis implicates schizophrenia susceptibility genes and enriches putatively functional rare genetic variants.
Duan J, Sanders AR, Moy W, Drigalenko EI, Brown EC, Freda J, Leites C, Göring HH; MGS; Gejman PV.
Duan J, et al. Among authors: leites c.
Hum Mol Genet. 2015 Aug 15;24(16):4674-85. doi: 10.1093/hmg/ddv199. Epub 2015 May 28.
Hum Mol Genet. 2015.
PMID: 26022996
Free PMC article.
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Open Chromatin Profiling in hiPSC-Derived Neurons Prioritizes Functional Noncoding Psychiatric Risk Variants and Highlights Neurodevelopmental Loci.
Forrest MP, Zhang H, Moy W, McGowan H, Leites C, Dionisio LE, Xu Z, Shi J, Sanders AR, Greenleaf WJ, Cowan CA, Pang ZP, Gejman PV, Penzes P, Duan J.
Forrest MP, et al. Among authors: leites c.
Cell Stem Cell. 2017 Sep 7;21(3):305-318.e8. doi: 10.1016/j.stem.2017.07.008. Epub 2017 Aug 10.
Cell Stem Cell. 2017.
PMID: 28803920
Free PMC article.
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MicroRNA-9 and microRNA-326 regulate human dopamine D2 receptor expression, and the microRNA-mediated expression regulation is altered by a genetic variant.
Shi S, Leites C, He D, Schwartz D, Moy W, Shi J, Duan J.
Shi S, et al. Among authors: leites c.
J Biol Chem. 2014 May 9;289(19):13434-44. doi: 10.1074/jbc.M113.535203. Epub 2014 Mar 27.
J Biol Chem. 2014.
PMID: 24675081
Free PMC article.
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Open chromatin dynamics reveals stage-specific transcriptional networks in hiPSC-based neurodevelopmental model.
Zhang S, Moy W, Zhang H, Leites C, McGowan H, Shi J, Sanders AR, Pang ZP, Gejman PV, Duan J.
Zhang S, et al. Among authors: leites c.
Stem Cell Res. 2018 May;29:88-98. doi: 10.1016/j.scr.2018.03.014. Epub 2018 Mar 31.
Stem Cell Res. 2018.
PMID: 29631039
Free PMC article.
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