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Exploring the interaction between siRNA and the SMoC biomolecule transporters: implications for small molecule-mediated delivery of siRNA.
Gooding M, Tudzarova S, Worthington RJ, Kingsbury SR, Rebstock AS, Dube H, Simone MI, Visintin C, Lagos D, Quesada JM, Laman H, Boshoff C, Williams GH, Stoeber K, Selwood DL. Gooding M, et al. Among authors: simone mi. Chem Biol Drug Des. 2012 Jan;79(1):9-21. doi: 10.1111/j.1747-0285.2011.01249.x. Epub 2011 Nov 4. Chem Biol Drug Des. 2012. PMID: 21981778
Selective Inhibition of the Mitochondrial Permeability Transition Pore Protects against Neurodegeneration in Experimental Multiple Sclerosis.
Warne J, Pryce G, Hill JM, Shi X, Lennerås F, Puentes F, Kip M, Hilditch L, Walker P, Simone MI, Chan AW, Towers GJ, Coker AR, Duchen MR, Szabadkai G, Baker D, Selwood DL. Warne J, et al. Among authors: simone mi. J Biol Chem. 2016 Feb 26;291(9):4356-73. doi: 10.1074/jbc.M115.700385. Epub 2015 Dec 17. J Biol Chem. 2016. PMID: 26679998 Free PMC article.
Endothelial C-type natriuretic peptide maintains vascular homeostasis.
Moyes AJ, Khambata RS, Villar I, Bubb KJ, Baliga RS, Lumsden NG, Xiao F, Gane PJ, Rebstock AS, Worthington RJ, Simone MI, Mota F, Rivilla F, Vallejo S, Peiró C, Sánchez Ferrer CF, Djordjevic S, Caulfield MJ, MacAllister RJ, Selwood DL, Ahluwalia A, Hobbs AJ. Moyes AJ, et al. J Clin Invest. 2014 Sep;124(9):4039-51. doi: 10.1172/JCI74281. Epub 2014 Aug 8. J Clin Invest. 2014. PMID: 25105365 Free PMC article.
Warburg Effect Targeting Co(III) Cytotoxin Chaperone Complexes.
Glenister A, Chen CKJ, Paterson DJ, Renfrew AK, Simone MI, Hambley TW. Glenister A, et al. J Med Chem. 2021 Mar 11;64(5):2678-2690. doi: 10.1021/acs.jmedchem.0c01875. Epub 2021 Feb 23. J Med Chem. 2021. PMID: 33621096
996 results