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Page 1
Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases.
Gusev A, Lee SH, Trynka G, Finucane H, Vilhjálmsson BJ, Xu H, Zang C, Ripke S, Bulik-Sullivan B, Stahl E; Schizophrenia Working Group of the Psychiatric Genomics Consortium; SWE-SCZ Consortium; Kähler AK, Hultman CM, Purcell SM, McCarroll SA, Daly M, Pasaniuc B, Sullivan PF, Neale BM, Wray NR, Raychaudhuri S, Price AL; Schizophrenia Working Group of the Psychiatric Genomics Consortium; SWE-SCZ Consortium. Gusev A, et al. Am J Hum Genet. 2014 Nov 6;95(5):535-52. doi: 10.1016/j.ajhg.2014.10.004. Epub 2014 Nov 6. Am J Hum Genet. 2014. PMID: 25439723 Free PMC article.
Highly scalable genotype phasing by entropy minimization.
Gusev A, Măndoiu II, Paşaniuc B. Gusev A, et al. IEEE/ACM Trans Comput Biol Bioinform. 2008 Apr-Jun;5(2):252-61. doi: 10.1109/TCBB.2007.70223. IEEE/ACM Trans Comput Biol Bioinform. 2008. PMID: 18451434
Systematic haplotype analysis resolves a complex plasma plant sterol locus on the Micronesian Island of Kosrae.
Kenny EE, Gusev A, Riegel K, Lütjohann D, Lowe JK, Salit J, Maller JB, Stoffel M, Daly MJ, Altshuler DM, Friedman JM, Breslow JL, Pe'er I, Sehayek E. Kenny EE, et al. Among authors: gusev a. Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13886-91. doi: 10.1073/pnas.0907336106. Epub 2009 Aug 10. Proc Natl Acad Sci U S A. 2009. PMID: 19667188 Free PMC article.
Increased power of mixed models facilitates association mapping of 10 loci for metabolic traits in an isolated population.
Kenny EE, Kim M, Gusev A, Lowe JK, Salit J, Smith JG, Kovvali S, Kang HM, Newton-Cheh C, Daly MJ, Stoffel M, Altshuler DM, Friedman JM, Eskin E, Breslow JL, Pe'er I. Kenny EE, et al. Among authors: gusev a. Hum Mol Genet. 2011 Feb 15;20(4):827-39. doi: 10.1093/hmg/ddq510. Epub 2010 Nov 30. Hum Mol Genet. 2011. PMID: 21118897 Free PMC article.
Quantifying missing heritability at known GWAS loci.
Gusev A, Bhatia G, Zaitlen N, Vilhjalmsson BJ, Diogo D, Stahl EA, Gregersen PK, Worthington J, Klareskog L, Raychaudhuri S, Plenge RM, Pasaniuc B, Price AL. Gusev A, et al. PLoS Genet. 2013;9(12):e1003993. doi: 10.1371/journal.pgen.1003993. Epub 2013 Dec 26. PLoS Genet. 2013. PMID: 24385918 Free PMC article.
Genome-wide mapping of IBD segments in an Ashkenazi PD cohort identifies associated haplotypes.
Vacic V, Ozelius LJ, Clark LN, Bar-Shira A, Gana-Weisz M, Gurevich T, Gusev A, Kedmi M, Kenny EE, Liu X, Mejia-Santana H, Mirelman A, Raymond D, Saunders-Pullman R, Desnick RJ, Atzmon G, Burns ER, Ostrer H, Hakonarson H, Bergman A, Barzilai N, Darvasi A, Peter I, Guha S, Lencz T, Giladi N, Marder K, Pe'er I, Bressman SB, Orr-Urtreger A. Vacic V, et al. Among authors: gusev a. Hum Mol Genet. 2014 Sep 1;23(17):4693-702. doi: 10.1093/hmg/ddu158. Epub 2014 May 19. Hum Mol Genet. 2014. PMID: 24842889 Free PMC article.
Leveraging population admixture to characterize the heritability of complex traits.
Zaitlen N, Pasaniuc B, Sankararaman S, Bhatia G, Zhang J, Gusev A, Young T, Tandon A, Pollack S, Vilhjálmsson BJ, Assimes TL, Berndt SI, Blot WJ, Chanock S, Franceschini N, Goodman PG, He J, Hennis AJ, Hsing A, Ingles SA, Isaacs W, Kittles RA, Klein EA, Lange LA, Nemesure B, Patterson N, Reich D, Rybicki BA, Stanford JL, Stevens VL, Strom SS, Whitsel EA, Witte JS, Xu J, Haiman C, Wilson JG, Kooperberg C, Stram D, Reiner AP, Tang H, Price AL. Zaitlen N, et al. Among authors: gusev a. Nat Genet. 2014 Dec;46(12):1356-62. doi: 10.1038/ng.3139. Epub 2014 Nov 10. Nat Genet. 2014. PMID: 25383972 Free PMC article.
532 results