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The activity of Gli transcription factors is essential for Kras-induced pancreatic tumorigenesis.
Rajurkar M, De Jesus-Monge WE, Driscoll DR, Appleman VA, Huang H, Cotton JL, Klimstra DS, Zhu LJ, Simin K, Xu L, McMahon AP, Lewis BC, Mao J. Rajurkar M, et al. Among authors: cotton jl. Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):E1038-47. doi: 10.1073/pnas.1114168109. Epub 2012 Apr 9. Proc Natl Acad Sci U S A. 2012. PMID: 22493246 Free PMC article.
Tead and AP1 Coordinate Transcription and Motility.
Liu X, Li H, Rajurkar M, Li Q, Cotton JL, Ou J, Zhu LJ, Goel HL, Mercurio AM, Park JS, Davis RJ, Mao J. Liu X, et al. Among authors: cotton jl. Cell Rep. 2016 Feb 9;14(5):1169-1180. doi: 10.1016/j.celrep.2015.12.104. Epub 2016 Jan 28. Cell Rep. 2016. PMID: 26832411 Free PMC article.
YAP/TAZ Activation Drives Uveal Melanoma Initiation and Progression.
Li H, Li Q, Dang K, Ma S, Cotton JL, Yang S, Zhu LJ, Deng AC, Ip YT, Johnson RL, Wu X, Punzo C, Mao J. Li H, et al. Among authors: cotton jl. Cell Rep. 2019 Dec 3;29(10):3200-3211.e4. doi: 10.1016/j.celrep.2019.03.021. Cell Rep. 2019. PMID: 31801083 Free PMC article.
Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription.
Li Q, Sun Y, Jarugumilli GK, Liu S, Dang K, Cotton JL, Xiol J, Chan PY, DeRan M, Ma L, Li R, Zhu LJ, Li JH, Leiter AB, Ip YT, Camargo FD, Luo X, Johnson RL, Wu X, Mao J. Li Q, et al. Among authors: cotton jl. Cell Stem Cell. 2020 May 7;26(5):675-692.e8. doi: 10.1016/j.stem.2020.03.002. Epub 2020 Apr 6. Cell Stem Cell. 2020. PMID: 32259481 Free PMC article.
Deletion of Lats1/2 in adult kidney epithelia leads to renal cell carcinoma.
Carter P, Schnell U, Chaney C, Tong B, Pan X, Ye J, Mernaugh G, Cotton JL, Margulis V, Mao J, Zent R, Evers BM, Kapur P, Carroll TJ. Carter P, et al. Among authors: cotton jl. J Clin Invest. 2021 Jun 1;131(11):e144108. doi: 10.1172/JCI144108. J Clin Invest. 2021. PMID: 34060480 Free PMC article.
41 results